| Cancer, the stealthy enemy within, could one day betray its own presence by glowing green. Barely a week goes by without green fluorescent protein, known to its friends as 'GFP', playing a starring role in a science story. This week, researchers announce in the Proceedings of the National Academy of Sciences, 2000, vol. 97, no. 3, that they have used GFP to watch tumours grow and spread through the bodies of live mice simply by shining blue light on them. Meng Yang of AntiCancer Inc, San Diego, California, and colleagues, have been experimenting with GFP as an alternative to existing cancer imaging methods. If the technique can make it from the lab to the clinic it may pave the way for better detection and tracking of the earliest stages of cancer. GFP is a protein that fluoresces under UV or blue light with eerie greenish glow. External images of B16F0-GFP bone metastasis. In the proximal tibia of the left hind leg of C57BL/6 mouse
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