Leica AM TIRF

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TIRF (Total Internal Reflection Fluorescence) microscope system

TIRF Microscope System

Overview

Leica’s TIRF system features a dynamic scanner that can be used to precisely position the laser beam and determine the exact penetration depth of the evanescent field. The powerful Leica AF6000 fluorescence software offers full control of the TIRF system. All microscope functions and many analysis tools are included.
The precise orientation of the laser beam is controlled through the Leica AF6000 software in a highly precise, yet easy-to-use way. This high level of interaction through the changing of the penetration depth and the direction of the evanescent wave, while maintaining homogeneity and image quality, reveals additional structural information that would otherwise remain hidden.