How can it be avoided that sections are compressed/wrinkled or even jammed? FAQ Report You might use a dull blade/knife: Please use another area of the cutting edge or a new blade/knife. The specimen might be too warm: Please cool the specimen prior to sectioning by using a cold plate, iced water or ice cubes. The sectioning speed might be too high: Please work at a slower sectioning speed.Thin sections require a slow cutting speed. The clearance angle is too high: Lower systematically the clearance angle. The clearance angle of the knife or blade is too small: Systematically change to higher clearance angle. The knife edge or back of rear plate of the disposable blade holder might be contaminated with paraffin: Please clean both with a smooth cloth moistened with a non-solvent containing cleaning reagent such as Paraguard. Stroke the cloth in an upward motion away from the blade edge, not down towards the blade edge. Choose a value of retraction. The front pressure plate of the knife holder is not clamping properly (applies only to the knife holder E of the RM2100 series) -> leaf springs on the inside of the front pressure plate might be worn: Replace the leaf spring. Replace the locking lever (a Technical Service call is required). The blade cutting edge is not parallel with the pressure plate (applies only to the knife holder of the RM2100 series): Adjust the pressure plate with set screws at bottom of knife holder. Turn the screws until the blade is parallel to the top of the pressure plate. When the blade is parallel with the pressure plate, the base line of the blade should line up with the top of the pressure plate after being clamped.