The term photomanipulation encompasses a range of techniques that utilize the properties of fluorescent molecules to initiate events and observe how dynamic complexes behave over time in living cells. By precisely adjusting sample labeling, biological activity, local chemical environments and in some instances, physically destroying parts of the specimen, researchers are able to access additional layers of information from their living cells.
Whether bleaching, activating, converting, ablating or combining techniques, researchers need to have a system fully capable of performing and capturing events in high resolution.
Fluorescence Recovery After Photobleaching (FRAP) experiments require fast yet gentle and accurate bleaching of specific regions of interest (ROIs).
FRAP experiments typically are used in biological studies of cellular kinetics, such as membrane diffusion and protein binding.
Utilize the latest advances in photoswitchable fluorescent proteins.
By selectively activating regions of your cells, you can precisely follow how specific molecules behave in cells over time.
The Infinity Scanner gives you full flexibility to choose the wavelength, size, and shape of your activation regions.
With full integration into LAS X software, you can design and perform photoactivation experiments with the ease of a fully integrated system.