For the best result during screening, sorting, manipulation, and imaging you need to see details and structures to make the right decisions for your next steps in research.
Known for outstanding optics and superb resolution, stereo microscopes and transmitted light bases from Leica are the preferred choice of researchers worldwide.
Do you struggle to see finest pigments and structural differences in your zebrafish? The identification of the right phenotype is crucial and can be demanding.
See more details at first glance – Leica zebrafish screening solutions allow you to recognize finest structures and more colors even at low magnification. This means clear understanding of the nervous system, heart, blood vessels, and pigmentation.
Detecting xFP fusion proteins can be very challenging. You try to keep the expression physiologically low for realistic protein levels. Signals are therefore faint and hard to identify.
In this situation your microscope solution should not be working against you with high levels of autofluorescence, e.g. from lens glue, glass, and the LED of your microscope base.
This results in a clear and strong fluorescence signal against a noise-free, black background.
Leica stereo microscopes allow easy orientation in 3D. This ensures that you see exactly where your tools are, so you don’t accidently injure your model organism.
Functional imaging is one of the most demanding tasks in the laboratory. Leica supports you with fully automated stereo microscopes, like the M205 FA.
With the fully automated TL5000 Ergo transmitted light base from Leica, functional imaging brings out the best of your fish. It provides highest NA of 0.9 and adjusts the aperture automatically to the zoom, in order to eliminate stray light.