Origin™ IHC antibodies

Enjoy the confidence of knowing that your clones are backed by in-house reagent development and applications expertise. Use trusted and familiar Novocastra IHC clones on your Ventana® automated stainer.

Original – many Origin cell lines developed and held exclusively by Leica Microsystems
Proven – independent lot-to-lot verification with equivalent Ventana products
Cost effective – the Origin range provides a competitive alternative

It’s your choice

Over 20 commonly used IHC antibodies.


bcl-2 Oncoprotein Novocastra Antigen Background Bcl-2 is a member of a family of proteins that are involved in apoptosis. Bcl-2 is an integral inner mitochondrial...	CD1a Novocastra Antigen Background CD1a is a protein of 43 to 49 kD expressed on dendritic cells and cortical thymocytes. CD1a antigen expression has been...	CD3 Novocastra Antigen Background The CD3 molecule consists of five different polypeptide chains with molecular weights ranging from 16 to 28 kD. The CD3...	CD5 Novocastra Antigen Background CD5 antigen is reported to be expressed on 95 percent of thymocytes and 72 percent of peripheral blood lymphocytes. ...


CD8 Novocastra Antigen Background The CD8 molecule is composed of two chains and has a molecular weight of 32 kD. It is found on a T cell subset of normal...	CD10 Novocastra Antigen Background CD10 antigen, also called neprilysin, is a 100 kD cell surface metalloendopeptidase which inactivates a variety of...	CD23 Novocastra Antigen Background The CD23 molecule is the low affinity IgE receptor found on B cells.It is a membrane glycoprotein of 45 kD and is reported...	CD79a Novocastra Antigen Background The CD79 complex is a disulfide-linked heterodimer which is non-covalently associated with membrane-bound immunoglobulins...


Cytokeratin Novocastra Antigen Background The expression of different cytokeratins in epithelial-derived tumors and the general tendency towards maintenance of...	Desmin Novocastra Antigen Background NCL-DES-DERII reacts with an 18 kD rod piece of the intermediate filament protein desmin (53 kD) in muscle cells. The...	Estrogen Receptor Novocastra Antigen Background Estrogen receptor (ER) content of breast cancer tissue is an important parameter in the prediction of prognosis and...	Ki67 Novocastra Antigen Background The Ki67 antigen is a nuclear protein which is expressed in all active parts of the cell cycle (G1, S, G2 and mitosis) but...


Progesterone Receptor Novocastra Antigen Background The human progesterone receptor (PR) is expressed as two isoforms, PRA (94 kD) and PRB (114 kD), which function as...	Synaptophysin Novocastra Antigen Background Synaptophysin is an integral membrane glycoprotein with a molecular weight of 38 kD. It is reported to occur in...	Terminal Deoxynucleotidyl Transferase Novocastra Antigen Background Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase of 58 kD located in the cell nucleus which catalyzes the...