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Leica TCS SP8: Affordable at Entry-Level and Futureproof as your Needs Expand

From routine imaging to live cell research, from super-sensitivity to super-resolution, from multiphoton imaging to CARS – whatever your research, Leica Microsystems has the confocal for your application.

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Get in touch with our Confocal Microscopy experts and find the solution that matches your needs.

1. Sensitivity by Design

Many components of the standard scan head design contribute to photon-efficiency, such as new scan optics, CS2 objectives, LIAchroic beam splitters and SP detection to name a few. The result are brilliant imagery, flexibility for emerging experiments and increased sample viability.

FOV Scanner

  • See full specimen in one shot (time saved on stitching)
  • Increased time resolution
  • Higher throughput in screening experiments

CS2 Objectives

  • Improved color correction throughout the whole field of view
  • Perfect VIS – 405 overlay for best colocalization results


  • High suppression of excitation light for high contrast
  • Custom designed low incident angle dichroics
  • Cost efficient beam splitting

Spectral Detector

  • Gapless emission bands for faithful rendition of fluorescence spectral
  • Multi-band spectrophotometer
  • Prism-based dispersion for highest efficiency
  • Free from photon waste

2. Ready to Grow – Flexible to Match Future Requirements

As new scientific approaches unfold, so too do the instrumentation requirements to support them. With the Leica TCS SP8 you will be prepared for the new directions your research will take in the future. Leica Microsystems always ensures the path is open for the future, to help your confocal grow with changes in your experiments.

  • STED

  • MP

  • CARS

  • SMD

3. Compact Supply Unit – Entry to SP8 Class

What do you do if you are looking for a cost-efficient system that does the job but does not limit you? With its new compact supply unit, the Leica TCS SP8 allows you to buy into Leica Microsystems’ high-end platform whilst starting small. This supply unit, with its small-sized footprint, solid state lasers and LIAchroic scan head, teams with the Leica DMI6000 CEL microscope to give you everything you need for high-end research. Your compact Leica TCS SP8 will grow with your research to allow the addition of more imaging detectors, more excitation lasers, and a range of multiphoton options.

4. From Whole Organisms to Highest Level of Detail

  • Platynereis dumerillii, 2 month. Blue: nuclei, DAPI. Green: tubulin, FITC. Grey: phalloidin, Rhodamin. Red: serotonin, Cy5. 3D maximum projection of image taken with a 10x objective fully zoomed out at 5000 x 5000 scan format.
    Sample: courtesy of Dr. Antje Fischer and Dr. Detlef Arendt, Heidelberg, Germany
    Image courtesy of Dr. Stefan Terjung, EMBL, Heidelberg, Germany

  • Mosaicking (stitching) is available for samples larger than the field of view. Save time on stitching by covering the same area with a smaller number of images. Cover more ground, while preserving even the finest detail.

Large field – whole organism. By using an X2Y scan mirror architecture, Leica confocal systems support the largest field of view in point scanning. You can take images of whole animals or plants, often without stitching. See your specimens in widescreen.

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