Director of Molecular Biosensor and Imaging Center
Department of Biological Sciences, Carnegie Mellon University, Pittsburgh / US
We develop fluorescent biosensors toolkits for pathways of living cells, focussing on smart biosensors for high throughput methods. Our biosensor platform consists of Fluorescence Activating Proteins (FAPs) that bind fluorogen dyes with large fluorescence increases.
Sensors have been developed to rapidly and selectively track FAP labeled proteins such as GPCRs. This platform is proving promising for developing calcium, pH, sodium, potassium and redox sensors that will emit signals only from investigator-targeted regions of a cell. Sensors for protein-protein interactions and protein modification are in progress.
The members of the Scientific Advisory Board UK -
Prof. Paul French (Imperial College London), Prof. Antony Galione (Oxford Univ.), Dr. Jim Haseloff (Cambridge Univ.), Prof. David Klenerman (Cambridge Univ.), Prof. Gero Miesenboeck (Oxford Univ.), Prof. Tony Ng (King’s College London), Dr. Violaine Sée, Dr. Bob Burgoyne, Prof. Alexei Tepikin (Liverpool Univ.), Prof. Mike White (Manchester Univ.), Prof. Keith Willison (Institute of Cancer Research London), Prof. Tony Wilson (Oxford Univ.), and Dr. Thomas Zapf (Leica Microsystems)
- cordially invite you to meet Alan Waggoner at the post lecture receptions for personal discussion.
All lectures are free of charge. For organizational reasons please RSVP by e-mail to LSF@leica-microsystems.com.