New developments in Multi-photon microscopy (MPM) allow the direct observation of the behavior of individual cells in vivo in real time. In mammary tumors MPM demonstrates that invasive/migratory carcinoma cells form migratory streams and intravasate when associated with macrophages.
Taking advantage of this macrophage tropism allows imaging guided collection of migratory competent macrophages and tumor cells as live cells directly from the primary tumor.
Expression profiling of these co-migratory tumor cells and macrophages has led to the surprising conclusion that both cell types exhibit embryonic expression patterns.
Leica Scientific Forum San Diego
Monday, November 18, 2013 – 4:00pm, Chair: Mark Ellisman
Venue: Liebow Auditorium - Biomedical Sciences Bldg, Second Flr - UCSD, 9500 Gilman Dr, La Jolla, CA 92093
Leica Scientific Forum Los Angeles & CNSI NanoSystems Seminar
Tuesday, November 19, 2013 – 4:00pm, Chair: Shimon Weiss
Venue: Auditorium of the California NanoSystems Institute (CNSI), UCLA, Building 114, 570 Westwood Plaza, Los Angeles, CA 90095
Leica Scientific Forum San Francisco
Wednesday, November 20, 2013 – TIME CHANGED: 3:00pm, Chair: Arnold Kriegstein
Venue: Helen Diller Family Cancer Research Building, 1450 3rd St., San Francisco, CA 94158
You are cordially invited to meet John Condeelis at the post lecture receptions for personal discussion.
All lectures are free of charge. For organizational reasons, please kindly RSVP by e-mail to Sandra Ebert:
The members of the Scientific Advisory Board US-West Coast:
Prof. Roger Tsien (UCSD), Prof. Mark Ellisman (UCSD), Prof. Shimon Weiss (UCLA), Prof. Katsushi Arisaka (UCLA), Prof. Arnold Kriegstein (UCSF), Prof. Michael Stryker (UCSF) & Dr. Thomas Zapf (Leica Microsystems)