Low dark noise
Neuromuscular junction in Drosophila melanogaster labeled with Bruchpilot::mStrawberry. The background of the PMT image is blurred by residual noise amplified by the maximum projection, while the HyD images is devoid of noise.
Courtesy of Stefan J. Sigrist, Institut f. Biologie/Genetik, Freie Universität Berlin, Berlin, Germany.
Increased cell viability
Live yeast cells double-labeled with eGFP at, both, the nuclear envelope and the telomere.
Courtesy of Susan M. Gasser, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
High sensitivity for single molecules
These molecules were embedded in PFA. They were imaged using a Leica TCS SP5 II equipped with AOBS and white light laser.
Courtesy of Christian Hellriegel, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.