News for Leica DM5500 B
Scanning Stage for Leica DM4000-6000 B Upright Research Microscopes
23 September 2011
New motorized scanning stage 100x100 mm, developed especially for applications with upright research microscopes Leica DM4000-6000 B for automatic and high-precision positioning of samples
- Flat design due to lowered motor axis
- For reflected light/fluorescence and transmitted light applications
- New stage insert for 2 glass slides 3”x 2” (76 x 52 mm) for precise holding
- Motor cable connection located ergonomically on the back right side
- Integrated in Leica Microsystems Software and control units
(can be operated by Leica Software/SmartMove/STP6000) - Adjustable limit switches for individual adjustment of the travel range of the stage
Intelligent Structured Illumination Microscopy by Leica Microsystems
11 May 2010

Kidney section (mouse). Maximum projection of a stack of 65 single images. Green: Glomeruli and convoluted tubules (wheat germ agglutinin Alexa Fluor® 488); blue: cell nuclei (DAPI).
The Smart Solution for Superior Contrast in Fluorescence Imaging
Wetzlar, Germany. Resolution and contrast are crucially important for fluorescence applications in widefield microscopy. Undesired haze effects that reduce contrast can be minimized by using the smart principle of structured illumination. The result: fluorescence images with excellent contrast, superb axial resolution and ultra-sharp 2D sections of the specimen.
Intelligent Structured Illumination Microscopy from Leica Microsystems uses the proven OptiGrid® technique. Working in harmony with Leica’s superior quality optics, the aperture diaphragm integrated with the fluorescence light path also enhances contrast. The automatic focus function of the OptiGrid® keeps the grid structure in focus, from UV to IR light.
A unique feature of this development is that the same OptiGrid® module can be used both for upright and for inverted Leica research microscopes. Furthermore, there is no need to change the grid, as one optimized grid covers all magnifications from 10x to 100x, which offers convenience, avoids errors, and saves valuable time.
Intelligent Structured Illumination Microscopy from Leica Microsystems gives you a complete system from a single source: The OptiGrid® module integrated with Leica research microscopes is controlled by intuitive Leica MM AF software and complemented by a wide selection of fluorescence cameras.
Leica Structured Illumination is available for the inverted research microscopes Leica DMI4000 B and DMI6000 B, and the upright research microscopes Leica DM5000 B, DM5500 B and DM6000 B.
