News for Leica DM5000 B
Scanning Stage for Leica DM4000-6000 B Upright Research Microscopes
23 September 2011
New motorized scanning stage 100x100 mm, developed especially for applications with upright research microscopes Leica DM4000-6000 B for automatic and high-precision positioning of samples
- Flat design due to lowered motor axis
- For reflected light/fluorescence and transmitted light applications
- New stage insert for 2 glass slides 3”x 2” (76 x 52 mm) for precise holding
- Motor cable connection located ergonomically on the back right side
- Integrated in Leica Microsystems Software and control units
(can be operated by Leica Software/SmartMove/STP6000) - Adjustable limit switches for individual adjustment of the travel range of the stage
Intelligent Structured Illumination Microscopy by Leica Microsystems
11 May 2010

Kidney section (mouse). Maximum projection of a stack of 65 single images. Green: Glomeruli and convoluted tubules (wheat germ agglutinin Alexa Fluor® 488); blue: cell nuclei (DAPI).
The Smart Solution for Superior Contrast in Fluorescence Imaging
Wetzlar, Germany. Resolution and contrast are crucially important for fluorescence applications in widefield microscopy. Undesired haze effects that reduce contrast can be minimized by using the smart principle of structured illumination. The result: fluorescence images with excellent contrast, superb axial resolution and ultra-sharp 2D sections of the specimen.
Intelligent Structured Illumination Microscopy from Leica Microsystems uses the proven OptiGrid® technique. Working in harmony with Leica’s superior quality optics, the aperture diaphragm integrated with the fluorescence light path also enhances contrast. The automatic focus function of the OptiGrid® keeps the grid structure in focus, from UV to IR light.
A unique feature of this development is that the same OptiGrid® module can be used both for upright and for inverted Leica research microscopes. Furthermore, there is no need to change the grid, as one optimized grid covers all magnifications from 10x to 100x, which offers convenience, avoids errors, and saves valuable time.
Intelligent Structured Illumination Microscopy from Leica Microsystems gives you a complete system from a single source: The OptiGrid® module integrated with Leica research microscopes is controlled by intuitive Leica MM AF software and complemented by a wide selection of fluorescence cameras.
Leica Structured Illumination is available for the inverted research microscopes Leica DMI4000 B and DMI6000 B, and the upright research microscopes Leica DM5000 B, DM5500 B and DM6000 B.
Brilliant, Easy Imaging at the Speed of Light!
11 October 2007

The perfect imaging solution for all scientific research: the new generation Leica Digital Microscopes for biological and materials sciences
The perfect imaging solution for all scientific research: the new generation Leica Digital Microscopes for biological and materials sciences
Wetzlar, Germany. Leica Microsystems introduces an enhanced imaging solution for biological and materials sciences. Quickly and easily capture excellent images and achieve reliable, reproducible research results with the new generation Leica Digital Microscopes. The Leica DM4000 B through DM6000 B series for biological sciences, and the Leica DM4000 M and Leica DM6000 M Digital Microscopes for material sciences and industrial quality analysis, streamlines important work processes. The image brilliance and operational speed of the integrated imaging system are unparalleled in this class of microscope. Leica’s Intelligent Automation, made possible via the most sophisticated control electronics, ensures reproducible, reliable results. New components, such as the external Leica STP6000 SmartTouch Panel, give the researcher a new level of convenient microscope control.
Convenient microscope control
The Leica DM4000 is the only microscope of its class with a status display that shows all settings at a glance and allows individual function modes for specific applications. With the Leica DM5000 through DM6000, the user can set the automated functions using the new Leica SmartTouch color touchscreen, which is built into the stand. As a result, different user profiles can be saved and recalled at the push of a button. With the new, optional Leica STP6000 SmartTouch Panel, the Leica Digital Microscopes can also be operated via remote control. These convenient controls feature the same user interface for direct, intuitive operation as the Leica Application Suite Software (LAS). All motorized modules of the microscopes can also be controlled on the PC via the LAS software.
Save precious time
Working with microscopes has never been so easy. Complex processes can be automated according to individual specifications. In this way the user not only saves a great deal of time during familiarization, but also during his or her daily work. The microscopes can be operated intuitively, and all parameters can be automatically set and reproduced at any time. Leica’s unique method of changing contrast with the push of a button and the fully automated Differential Interference Contrast (DIC) make switching contrast techniques a fast and reliable process.
The perfect integrated system
Each research task has its own unique requirements. The microscope, camera, and LAS software modules for image processing and documentation integrate seamlessly and can be configured to best meet the scientist’s research needs, now and in the future. Due to the harmonized integration of the microscope, digital camera and software, Leica Microsystems offers an all-inclusive solution.
