Contrasting is one of the most critical steps of specimen preparation for electron microscopy. The double contrast method of ultrathin sections on grids with the heavy metals uranyl acetate and lead citrate is the standard routine contrasting technique for electron microscopy. To satisfy the scientific demand for reproducible, high-quality samples with low reagent consumption and safe working conditions for the user, Leica Microsystems offers the Leica EM AC20 automatic contrasting instrument. Within a sealed chamber, ultrathin sections are automatically contrasted with minimum user interaction.
Reproducible, high-quality samples with low reagent consumption and safe working conditions!