News for Leica S6 E

Leica S6 E

This video article describes a zebrafish model of acute kidney injury (AKI) upon intravenous microinjection of a nephrotoxicant.

Microinjections have been performed under a Leica S6 E stereo microscope.

Successful microinjection was verified by monitoring lucifer yellow dextran fluorescence in the heart of the zebrafish using a Leica M205 FA stereo microscope.

The article provides a detailed protocol for intravenous microinjection and can be transferred to other types of studies that require delivering soluble substances into the bloodstream of zebrafish larvae.

Click here to see the video about the zebrafish model for AKI from intravenous microinjection technique to visual measures of kidney disfunction.