Intra-operative fluorescence-guided tumor resection in oncology - 400 nm/blue Leica FL400

Leica M720 FL400 fluorescence module 400nm/blue

The Leica FL400* in combination with the active substance 5-ALA helps to see the tumor more clearly for a more complete resection of malignant glioma, while sparing healthy brain tissue.

Before surgery, the patient drinks the 5-ALA solution. The aminolevulinic acid is absorbed by the cells in the body, whereas the glioma cells take up more and convert 5-ALA into the fluorescent PPIX. When illuminated under blue light the PPIX in the tumor glows an intense red, while the normal tissue appears blue.

* The Leica FL400 is not approved for sale in the USA, Japan, and some other countries. Please contact your local Leica Microsystems sales representative for further information.

Your Advantages


Visible tumor margins Under Leica FL400 blue light mode the surgeon and the assistant can observe the vital tumor and the anatomy in high-contrast, bright, and in the full field of view. This means resection is easier to do as fewer changes to the white light mode are necessary.	Quick and easy handling Changing observation modes is easy. To switch from white light view to blue light fluorescence mode and back requires only the click of a button on the hand or the foot switch. This ensures quick handling and supports the surgical workflow at all times.
Videos in high-definition Leica Microsystems supports the surgeon with HD technology in all fluorescence configurations and modes - both in white and blue light mode of the Leica FL400. The result: high-quality images on the monitor display and in the records.	Modular design The fluorescence modules Leica FL400 and FL800 can be combined on the surgical microscopes M720 OH5 and M525 OH4 with standard and HD video cameras. This gives the surgeon the full benefit of all features in all configurations.


IntenseBlue - Leica M720 FL400 The compact design of the Leica M720 microscope combined with the FL400 module enables the surgeon to work in comfort in 5-ALA - and all other applications. Additionally, the system now requires only the intense 400 Watt built-in xenon light source to deliver a bright and clear fluorescence view.	DoubleBlue - Leica M525 FL400 The Leica M525 microscope combined with the FL400 module uses two light sources to create the best excitation, resulting in a bright fluorescence view. The 300 Watt xenon lamp is part of the microscope illumination, while the Karl Storz light source is dedicated to blue light fluorescence only.

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