Mechanical polishing can be time consuming and frustrating. It can also introduce unwanted artifacts when preparing cross-sectioned samples for electron backscatter diffraction (EBSD) in the scanning electron microscope (SEM) or light microscope investigation. In contrast, ion beam milling can eliminate undesirable artifacts that will hamper your analysis and interpretation.
Classical polarized light (compound) microscopes can only be used for prepared samples, because the working distance they offer is insufficient for whole samples. This means that thicker and bigger geological samples have to be sectioned and polished to fit under the limited working distance of a compound microscope.
The Leica DVM 6 provides outstanding image quality, extra working distance and allows geologists to work with polished and unpolished samples (micro mounts, fossils, drilled cores …), make 3D reconstructions of their surfaces and enables classical petrographic work as well.
For automotive manufacturers and auto parts suppliers, obtaining component cleanliness results rapidly, accurately, and reproducibly over the entire workflow is a significant advantage. Pall and Leica can make it easier.
The quality of steel is an essential topic in automotive, metalworking and building industries. To ensure the highest standards, an accurate and reliable Quality Assurance workflow for the inspection of non-metallic inclusions is crucial.
Grain size plays an essential role in the mechanical properties of materials. Learn how to overcome problems in sample preparation and how to analyze different materials like, steel, aluminium, titanium, copper and ceramics.
CRISPR has become one of the biologist’s favorite ways for deleting, replacing, or editing DNA, and much of the conversation about CRISPR-Cas9 has revolved around its potential for gene editing in health and disease. This webinar will showcase how CRISPR has also begun to revolutionize our understanding of how genomes work and will discuss the potential of CRISPR imaging tools to study genetic elements within living cells. Two leaders in this field, Gene Yeo from UCSD and Bo Huang from UCSF, discuss techniques, technology, and insights on CRISPR imaging.
In this webinar, we show that optical clearing drastically increases the signal-to-noise ratio and staining quality, thus enabling STED nanoscopy of the subtlest elements of the kidney. In this way we show that optical clearing is not only a sample preparation technique to consider when imaging large mm-scale samples, but could also be fruitful when imaging at the nanoscale. Furthermore, the increased transparency of the optically cleared sample enables volumetric 3D STED imaging at sub-diffraction-limited resolution.
The webinar will provide an overview of the latest advances in Cryo CLEM, which acts as a powerful interface by combining the best of the light and electron microscopy worlds to overcome their independent barriers and determine the location of fluorescent labelled structures within the landscape of an electron micrograph and showcase how Cryo CLEM adds additional value to quantitative 3D imaging and tomography.