CARS Microscopy
CARS (Coherent Anti-Stokes Raman Scattering) microscopy is a dye-free method which images structures by displaying the characteristic intrinsic vibrational contrast of their molecules. The crucial advantage of this method is that the sample remains almost unaffected. It does not require labeling but uses the spectroscopic properties of various chemical species found in organic material.
Related Topics
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Webinar
21. Nov 2011 Institutes: Academy of Sciences of the Czech Republic, Institute of Animal Physiology and Genetics, Liběchov, Chzech Republic, University Medical Center Utrecht, Hubrecht Institute-KNAW, The Netherlands, University of California, Irvine (UCI), Department of Chemistry, USAThe free online webinar presented by Leica Microsystems in association with BioOptics World took place on Thursday, December 1 2011. Register and view the webinar on demand. Read article
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Tutorial
04. Nov 2011 Institute: Leica Microsystems, Wetzlar, GermanyCARS overcomes the drawbacks of conventional staining methods by the intrinsic characteristics of the method. CARS does not require labeling because it is highly specific to molecular compounds which are based on vibrational contrast and chemical selectivity. The crucial advantage of this method is… Read article
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Tutorial
01. Nov 2011 Institute: Leica Microsystems, Wetzlar, GermanyCARS (Coherent Anti-Stokes Raman Scattering) microscopy is a dye-free method which images structures by displaying the characteristic intrinsic vibrational contrast of their molecules. The crucial advantage of this method is that the sample remains almost unaffected. This tutorial explains the… Read article
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Article
19. Oct 2011 Institute: Leica Microsystems, Wetzlar, GermanyCARS (Coherent Anti-Stokes Raman Scattering) microscopy is a dye-free method which images structures by displaying the characteristic intrinsic vibrational contrast of their molecules. The crucial advantage of this method is that the sample remains almost unaffected. Read article
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Article
13. Apr 2011 Institutes: Leica Microsystems, Wetzlar, Germany, University of California, Irvine (UCI), Department of Chemistry, USAIn recent years, new molecular imaging techniques, such as coherent anti-Stokes Raman scattering microscopy (CARS), have been developed for rapid vibrational imaging of living cells. Read article
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Tutorial
02. Nov 2010 Institute: Leica Microsystems, Wetzlar, GermanyThe most important drawback of single-photon and multiphoton confocal microscopy is the need to label the specimen. CARS (Coherent Anti-Stokes Raman Spectroscopy) addresses this issue because it is non-toxic, non-destructive, and minimally invasive. Read article
Useful Links
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Institutes
bernstein.harvard.edu/XieHome.html
Prof. Xiaoliang Sunney Xie, Havard Universitiy, Department of Chemistry and Chemical Biology
cms.uni-konstanz.de/zumbusch/
Prof. Andreas Zumbusch, University of Konstanz, Department of Chemistry
chem.ps.uci.edu/~potma/webpage_test.htm
Assistant Professor Eric Olaf Potma, Ph. D, University of California, Irvine (UCI)
Communities and Web Sources
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Social network for scientists
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Confocal Microscopy Mailing List, University of Minnesota
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Online magazine and community for molecular and cell biology researchers
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Resource for high-end scientific illustrations, images and animations
Search Engines and Data Bases
www.cellimagelibrary.org
Public resource database of images, videos, and animations of cells
harvester.fzk.de/harvester
Bioinformatic meta search engine for genes and proteins
www.gopubmed.com
Search interface for pubmed
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Development
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DMM Disease Models & Mechanisms
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International Journal of Life Science Methods
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Collection of Journals and Proceedings in Optics and Photonics
spie.org/x576.xml
SPIE - peer-reviewed journals on applied research in optics and photonics
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1864-0648
Journal of Biophotonics
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International, peer-reviewed, open-access, online publication
rspb.royalsocietypublishing.org/
Proceedings B - the Royal Society's biological research journal
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International Journal for microscopists
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News and features on biomedical microscopy
Organizations
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Microscopy Society of America
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ASCB American Society of Cell Biology
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