YouTube video by Leica Microsystems, August, 2014
As head of the imaging facility at the Leibniz Institute for Neurobiology in Magdeburg, Germany, Werner Zuschratter’s competence is in supporting scientists of the institute working on learning and memory research. Furthermore his facility also supports the Magedeburg University as well as other external researchers. His personal focus is on analyzing the neuronal network, meaning the contacts between nerve cells. Out of this reason he started doing super-resolution microscopy: “It gives us deeper insight into the synapses, into the synaptic machinery, into the molecules we would like to see. Before we could only do electron microscopy and now, with super-resolution, we also have access by light microscopy to the deeper structures inside the nerve system.”
Coming from the electron microscopy field Zuschratter’s view on the first super-resolution image he saw was rather unenthusiastic at first, but with time and the rise of 3D super-resolution microscopy he realized the potential of the new technique. Especially the 3D advancement he prognosticates will have a prosperous future. In his eyes the major forthcoming challenge will be the live cell imaging capability of super-resolution microscopy systems. But anyhow he predicts for super-resolution “in some years it will be the standard procedure.”
Teaming up with Leica Microsystems since more than 20 years he looks back to a good collaboration which he hopes to continue in the future.