Microscopy, Imaging and Analysis Solutions from Leica Microsystems

We shape the future by empowering users of our breakthrough optical and digital solutions to create a better, healthier world. For more than 175 years, we have been revealing the invisible with our market-leading technology in life science research, industry, medicine, forensics and education.

Revealing the Invisible for a Better and Healthier World.

Main Areas We Serve

Medical Microscopy

With a portfolio covering microsurgery disciplines including ophthalmology, neurosurgery, otolaryngology (ENT), plastic reconstructive surgery and dentistry, there is a surgical microscope from Leica to meet your needs.

Life Science Research

Leica Microsystems’ life science research microscopes support the imaging needs of the scientific community with advanced innovation and technical expertise for the visualization, measurement and analysis of microstructures.

Industrial Microscopy

Maximizing uptime and achieving targets efficiently help your bottom line. Leica Microscope solutions can give you insights into the smallest sample details as well as analyze, document, and report results fast and reliably.

Introducing Online Shopping

Find the Perfect Solution for Your Application Needs.

Access our extensive product catalog and enjoy a seamless online shopping experience. Explore and purchase pre-configured bundles in our Leica Microsystems shop.

Currently available only in the United States.

Advanced Imaging – DMi8 Inverted Microscope Platform

Streamline your complex workflows and generate high quality data.

Streamline your complex microscopy workflows with a platform that enables you to generate data with solutions that you can tailor to your research requirements and budget.

MyVeo All-In-One Surgical Visualization Headset

Stay focused, work comfortably, and enhance team collaboration in the OR.

Have you imagined what the future of surgery will look like? Reimagine how you see, how you move, and how you collaborate during surgery – MyVeo takes you beyond what you’ve imagined.

Ivesta 3 Greenough Stereo Microscopes

What if you could inspect with increased efficiency and work in a consistent way?

For manufacturers or suppliers, increasing efficiency for inspection is a priority. Optimize your visual inspection and rework while achieving reliable, consistent results.

Aivia AI Image Analysis Software

Access the future of AI microscopy

Aivia is a complete 2-to-5D image visualization, analysis and interpretation platform designed for the reliable processing and reconstruction of highly complex images.

Our Latest Articles

Read our latest articles

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments.

GLOW800 Augmented Reality Fluorescence used for real-time blood flow visualization in aneurysm clipping surgery

Aneurysm Clipping: Assessing Perforators in Real-time with AR Fluorescence

This article covers two aneurysm clipping cases highlighting the clinical benefits of GLOW800 Augmented Reality Fluorescence application in neurosurgery, based on insights from Prof. Tohru Mizutani,…

Prof. Fontana uses the Proveo 8 with EnFocus intraoperative OCT for his corneal surgery.

How does Real-time OCT Imaging Impact Precision in Corneal Surgery?

Corneal surgery is a highly specialized field. It requires great surgical precision to overcome challenges such as visualizing clearly the full anterior chamber, performing Descemet membrane peeling…

GLOW400 AR Fluorescence in anatomy view, image courtesy of Prof. Kondo

How to Achieve Brain Tissue Resection with GLOW400 AR

Intraoperative MRI is one form of real-time intraoperative visualization, but if more in-depth visualization to identify a tumor during surgery is wanted, intraoperative fluorescence diagnostics is…

How to Automatically Obtain Fluorescent Cells of Interest in a Block-face

Block-face created by automatic trimming under fluorescence. Mammalian cells of interest, stained with CellTrackerTM Green are visualized within the block-face using the UC Enuity equipped with the…

Automated Laser Microdissection for Proteome Analysis

Deep Visual Proteomics Provides Precise Spatial Proteomic Information

Despite the availability of imaging methods and mass spectroscopy for spatial proteomics, a key challenge that remains is correlating images with single-cell resolution to protein-abundance…

These images show the microstructure of a hard metal with 10% cobalt which is used for heavy-duty tools. The large increase in magnification of the right image (compared to the left) has a risk of being outside the useful range or, in other words, empty magnification.

What is Empty Magnification and How can Users Avoid it

The phenomenon of “empty magnification”, which can occur while using an optical, light, or digital microscope, and how it can be avoided is explained in this article. The performance of an optical…

Developing embryos of different species at different stages during the elongation of their posterior body axis, from left to right in developmental time. The labelled regions in red depict a region of undifferentiated cells called the tailbud, with the corresponding region generated from that tissue shaded in grey. Upper row: lamprey; middle row: catshark; bottom row, zebrafish. This figure has been adapted from the following publication: Steventon, B., Duarte, F., Lagadec, R., Mazan, S., Nicolas, J.-F., & Hirsinger, E. (2016). Species tailoured contribution of volumetric growth and tissue convergence to posterior body elongation in vertebrates. Development, 2016. 143(10):1732-41

How to Study Gene Regulatory Networks in Embryonic Development

Join Dr. Andrea Boni by attending this on-demand webinar to explore how light-sheet microscopy revolutionizes developmental biology. This advanced imaging technique allows for high-speed, volumetric…

Multiplexed Cell DIVE imaging of Adult Human Alzheimer’s brain tissue section demonstrating expression of markers specific to astrocytes (GFAP, S100B), microglia (TMEM119, IBA1), AD-associated markers (p-Tau217, β-amyloid) and immune cells such as CD11b+, CD163+, CD4+, and HLA-DRA+, clustered around the β-amyloid plaques.

Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…

Image of a tartaric-acid crystal taken with polarization microscopy. Tartaric acid, a diprotic, aldaric carboxylic acid, is a naturally occurring organic compound notably found in grapes.

The Polarization Microscopy Principle

Polarization microscopy is routinely used in the material and earth sciences to identify materials and minerals on the basis of their characteristic refractive properties and colors. In biology,…

A Guide to Spatial Biology

What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…

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