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Laser Microdissection LMD

Laser Microdissection, also known as LMD or LCM (Laser Capture Microdissection), is a contact- and contamination-free method for isolating specific single cells or entire areas of tissue from a wide variety of tissue samples. The thickness, texture and preparation technique of the original tissue are relatively unimportant. The dissectate is then available for further molecular biological methods such as PCR, real-time PCR, proteomics and other analytical techniques. Laser microdissection is now used in a large number of research fields, e.g. neurology, cancer research, plant analysis, forensics or climate research. The method is meanwhile also applied for manipulation of cell cultures or for microengraving of coverslips.

Our LMD Systems are perfect tools to optimize DNA-Workflows (Genomics), RNA-Workflows (Transcriptomics) and Proteomic-Workflows as they allow to precisely define and collect pure starting material for analysis under visual control.

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Please contact us if you would like to have personal expert advice on our microscopy solutions for laser microdissection.

Leica LMD6500 & LMD7000 Light Microscopes Products Home Leica Leica Microsystems

Laser Microdissection Systems Leica LMD6500 & LMD7000

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Replaced by Leica LMD6 & LMD7

Specimen collection by gravity – contact-free and contamination-free. Laser Microdissection (LMD) makes it possible to distinguish between relevant and non-relevant cells or tissues. It enables the researcher to obtain homogeneous, ultra-pure samples from heterogeneous starting material.

Researcher can selectively and routinely analyze regions of interest down to single cells from all kinds of tissues, even living cells from cell culture, to obtain results that are relevant, reproducible, and specific.

Leica Microsystems offers two systems for LMD: 
Leica LMD6500 and LMD7000

Learn more about Laser Microdissection applications on the knowledge portal on microscopy, Leica Science Lab.

Laser Microdissection System Leica LMD7000

Useful Links

LMD Software

Video Tutorials on Leica LMD Software

Publication List

LMD reference list for major application fields in life science research

Communities and Web Sources

www.researchgate.net/ Social network for scientists

bitesizebio.com Online magazine and community for molecular and cell biology researchers

www.somersault1824.com Resource for high-end scientific illustrations, images and animations

Search Engines and Data Bases

www.cellimagelibrary.org Public resource database of images, videos, and animations of cells

harvester.fzk.de/harvester Bioinformatic meta search engine for genes and proteins

www.gopubmed.com Search interface for pubmed

en.wikipedia.org/wiki/List_of_academic_databases_and_search_engines List of academic databases and search engines

scholar.google.com Beta of Google's search engine for scientific article abstracts

Journals

www.doaj.org/ Directory of open access journals

emboj.embopress.org/ The EMBO Journal

www.lifescied.org CBE-Life Sciences Education – an ASCB online journal

www.sciencemag.org/ Science

www.nature.com/ Nature

www.cell.com/ Biweekly publication of exceptional research articles

jcs.biologists.org/ Journal of Cell Science

dev.biologists.org/ Development

jeb.biologists.org/ The Journal of Experimental Biology

dmm.biologists.org/ DMM Disease Models & Mechanisms

www.biotechniques.com/ International Journal of Life Science Methods

www.opticsinfobase.org/ Collection of Journals and Proceedings in Optics and Photonics

spie.org/x576.xml SPIE - peer-reviewed journals on applied research in optics and photonics

onlinelibrary.wiley.com/journal/10.1002/(ISSN)1864-0648 Journal of Biophotonics

www.plosone.org/home.action International, peer-reviewed, open-access, online publication

rspb.royalsocietypublishing.org/ Proceedings B - the Royal Society's biological research journal

www.microscopy-analysis.com/ International Journal for microscopists

Organizations

www.microscopy.org/ Microscopy Society of America

www.eurmicsoc.org/ European Microscopy Society

www.rms.org.uk/ Royal Microscopical Society

www.ascb.org/ ASCB American Society of Cell Biology

www.biologists.com/cob_activities.html The company of biologists

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