Compound Microscope Solutions
Compound microscopes from Leica Microsystems are developed with the user in mind. Our instruments meet the highest demands whatever the application – from routine laboratory work to the research of multi-dimensional dynamic processes in living cells.
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For New Customers
Life Science Solutions
Inverted Laboratory Microscopes
- Live cell imaging
- Equipped with a 3 position fluorescence slider
- Conveniently monitor large cell culture flasks
Fluorescence Microscopes
- Flexible solution for advanced widefield research
- Fully configurable with manual to motorized components
- Increase your viewing area up to 10,000x
- Experiments up to 5 x faster
THUNDER
- Decode 3D biology in real time
- Blur-free images with fine details
- Optimized for large fields of view
- Z-stack images
Industrial Applications
Digital Microscopes
- 2D and 3D analysis
- Continuously encoded and calibrated zoom
- High quality objectives
Routine Inspection Microscopes
- Ease of use and reliable results even for untrained operators
- Various contrast modes: Brightfield, Darkfield, Differential Interference contrast, Polarization, Fluorescence
- Increased working distance to protect the sample
Materials Microscopes
Fully automated materials analysis
LED Illumination for all Contrast Modes
Reveal Hidden Details with High-definition Darkfield (HDF)
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Fluorescence is a process where a substance after having absorbed light (photons) emitts a radiation the wavelength (colour) of which is longer than that of the absorbed light, and where this…Read article
Fluorescence Recovery after Photobleaching with the Leica TCS SP2
Among all photobleaching experiments which have been described, fluorescence recovery after photobleaching (FRAP) is the most popular. It employs irradiation of a fluorophore in a living sample with a…Read article
Multi-photon Excitation Microscopy
Advanced microscopical techique for life science: multiphoton microscopy. Multi-photon excitation (MPE) microscopy plays a growing role among microscopical techniques utilized for studying biological…Read article
FRET Sensitized Emission Wizard Confocal
Förster Resonance Energy Transfer (FRET) is a technique, which allows insight into the interactions between proteins or molecules in proximities beyond light microscopic resolution.Read article
4D Photoactivation of pa-GFP in Living Cells Using Two-Photon Excitation Laser Scanning Microscopy
We report about two-photon activation of a photoactivatable derivative of the Aequorea Victoria green fluorescent protein (pa-GFP). This special form of the molecule increases its fluorescence…Read article
The History of Stereo Microscopy – Part I
The 17th century in Europe was marked by the Thirty Years' War (1618–1648). The population lived in constant fear and poverty. Marauding hordes wandered the countryside; failed harvests, plagues,…Read article
The History of Stereo Microscopy – Part II
For millennia, glass was admired for its beauty and the artful objects that could be created with it. With the rise of the exact sciences, however, researchers became more demanding with regard to…Read article
The History of Stereo Microscopy – Part III
Until the middle of the 19th century, microscopes were hand-crafted custom instruments. At the time, it was not possible to predict the properties of a lens in advance, so lenses were shaped and…Read article
CLEM: Combining the Strengths of Light and Electron Microscopy
In recent years light microscopy studies have been dominated by live cell imaging while electron microscopy has been used for high-resolution studies. Latterly, there has been increasing interest in…Read article
Detection and Characterization of Hepatic Engraftment of Embryonic Stem Derived Cells by Fluorescent Stereomicroscopy
Embryonic stem (ES) cells have been investigated as a potential replacement therapy for failed organs, such as the liver. However, detection of hepatic engraftment from candidate stem cells has been…Read article
In the Footsteps of Linnaeus – Microscopic Imaging in Marine Biodiversity Research
For the study of minute marine organisms such as free swimming larvae or bottom dwelling invertebrates it is a great advantage to have modern microscopic equipment in close proximity to the natural…Read article
Characterization of Photosynthetic Biofilms from Roman Catacombs via 3D Imaging and Subcellular Identification of Pigments
Artificial illumination can harm hypogean monuments by inducing the uncontrolled growth of photosynthetic biofilms (green sickness or maladie verte). With the aim of preventing biodeterioration or…Read article
Exploring Cell Logistics
Using TIRF microscopy, scientists have been able to take a closer look at intracellular transport processes with the example of the galactose-binding protein Galectin-3, which has been identified as a…Read article
Implementing Ergonomic Design for Microscope Workstations
This study evaluated the effect of an occupational therapy ergonomics intervention on the workstation design and body positioning of microscope workers at a fiber optics facility.Read article
Quality as Clear as Glass - Polarizing Microscopy in Glass Production
An exquisite beverage deserves a high-quality glass. Even the ancient Romans made artistically crafted drinking glasses. In the Middle Ages, Venetian glassmakers were famous for the purity of their…Read article
FusionOptics – Combines high resolution and depth of field for ideal 3D optical Images
A study carried out jointly by Leica Microsystems and the Institute of Neuroinformatics at the University of Zurich and Swiss Federal Institute of Technology provided the basis for an innovation in…Read article
Beware of "Empty" Magnification
This article explains how to avoid the phenomen of "empty magnification" in microscopy.Read article
A New FRAP/FRAPa Method for Three-Dimensional Diffusion Measurements Based on Multiphoton Excitation Microscopy
Quantitative measurement method based on FRAP and FRAPa using multiphoton microscopy. We present a new convenient method for quantitative three-dimensionally resolved diffusion measurements based on…Read article