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Science Lab

Science Lab

Science Lab

Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!
THUNDER image of brain-capillary endothelial-like cells derived from human iPSCs (induced pluripotent stem cells) where cyan indicates nuclei and magenta tight junctions.

Rapid Check of Live Stem Cells in Cell-culture Inserts Set in Multi-well Plates

See how efficient imaging of live iPSC stem cells within cell-culture inserts set in a multi-well plate can be done to evaluate the cells using a THUNDER Imager. Just read this article.
Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14.

Notable AI-based Solutions for Phenotypic Drug Screening

Learn about notable optical microscope solutions for phenotypic drug screening using 3D-cell culture, both planning and execution, from this free, on-demand webinar.

Erforschung der Virusreplikaton mit Fluoreszenzmikroskopie

Viren können mit Hilfe verschiedener Mikroskopietechniken untersucht werden. Je nach Vergrößerung und Auflösung des Mikroskops kann die Beobachtung auf Gewebe-, Zell- oder Virionenebene erfolgen.
Phase-contrast image of a MDCK-cell culture and its respective confluency measured by the Mateo TL microscope.

How to Determine Cell Confluency with a Digital Microscope

This article shows how to measure cell confluency in an easy and consistent way with Mateo TL, increasing confidence in downstream experiments.
Microscope image of cultured cells at the bottom of a dish.

How to do a Proper Cell Culture Quick Check

In order to successfully work with mammalian cell lines, they must be grown under controlled conditions and require their own specific growth medium. In addition, to guarantee consistency their growth…
Images of smooth muscle cells during wound healing. Courtesy L.S. Shankman, Ph.D., University of Virginia.

Studying Wound Healing of Smooth Muscle Cells

This article discusses how wound healing of cultured smooth muscle cells (SMCs) in multiwell plates can be reliably studied over time with less effort using a specially configured Leica inverted…
Single-cell Huh-7D12 spheroid imaged using a Leica SP8 DLS microscope system. The spheroid was clarified using the Sucrose protocol.

A Quality Metric for the Systematic Evaluation of Clearing Protocols

3D multicellular spheroids are of interest for studying tumor behavior and evaluating the response of pharmacologically active agents, because they mimic the in vivo tumor environment better than…
Mammalian cell culure. Phase contrast and fluorescence image.

Introduction to Mammalian Cell Culture

Mammalian cell culture is one of the basic pillars of life sciences. Without the ability to grow cells in the lab, the fast progress in disciplines like cell biology, immunology, or cancer research…

Applications of Laser Microdissection

Laser microdissection and laser micromanipulation are suitable for gaining a differentiated insight into the function of genes and proteins, and are used for a wide range of applications in…
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