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Leica HyD Confocal Microscopes Leica Leica Microsystems

Low dark noise

Neuromuscular junction in Drosophila melanogaster labeled with Bruchpilot::mStrawberry. The background of the PMT image is blurred by residual noise amplified by the maximum projection, while the HyD images is devoid of noise.

Courtesy of Stefan J. Sigrist, Institut f. Biologie/Genetik, Freie Universität Berlin, Berlin, Germany.

Increased cell viability

Live yeast cells  double-labeled with eGFP at, both, the nuclear envelope and the telomere.

Courtesy of Susan M. Gasser, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.

High sensitivity for single molecules

These molecules were embedded in PFA. They were imaged using a Leica TCS SP5 II equipped with AOBS and white light laser.

Courtesy of Christian Hellriegel, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.

High speed for C. elegans embryogenesis access

Three to four cell stage of Caenorhabditis elegans labeled by eGFP-tubulin.

Courtesy of Pierre Gönczy, École Polytechnique Fédérale Lausanne (EPFL), Lausanne, Switzerland