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Confocal Microscopes

Confocal microscopes from Leica Microsystems are partners in top level biomedical research and surface analysis in material science applications, offering unprecedented precision in three-dimensional imaging and exact examination of subcellular structures and dynamic processes.

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Contact a local imaging specialist for expert advice on the right Confocal Microscopy system for your needs.

Confocal Microscopes 9

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STED nanoscopy in all 3 dimensions

Leica TCS SP8 STED

STED Nanoscopes

STELLARIS - Confocal Microscope Platform

STELLARIS

With the STELLARIS confocal platform, we have re-imagined confocal microscopy to get you closer to the truth.

STED Microscope STELLARIS

STELLARIS STED & STELLARIS 8 STED

STELLARIS brings the full power and potential of STED in a fully integrated system.

Multiphoton Microscope STELLARIS 8 DIVE

STELLARIS 8 DIVE

STELLARIS 8 DIVE (Deep In Vivo Explorer) is a multiphoton microscope with spectrally tunable detection.

Leica TCS SP8 CARS Confocal Microscope-Label Free Imaging

Leica TCS SP8 CARS

Label-free imaging of native specimens

Leica TCS SPE with Leica DMi8 and climate chamber

Leica TCS SPE

The personal spectral confocal for daily research

Smart monitoring and service for scientific instruments RemoteCare

RemoteCare

Smart monitoring and service option for your microscope

Featured image

Mouse embryo mosaic image

High resolution mouse embryo mosaic image of 722 tiles containing 190 Megapixels. FLIM data fitted with four characteristic fluorescence lifetimes, color coded. Acquisition: 1:23 h. Analysis: 1:00 h

STELLARIS FALCON

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Confocal Microscopes Latest News

Factors to Consider When Selecting a Research Microscope

An optical microscope is often one of the central devices in a life-science research lab. It can be used for various applications which shed light on…

Leica Science Lab

How to Quantify Label-free Blood Flow

The application note “Label-free Blood Flow Quantification” is a guide for data acquisition and analysis of blood flow using label-free third harmonic…

Leica Science Lab

How Can Immunofluorescence Aid Virology Research?

Modern virology research has become as crucial now as ever before due to the global COVID-19 pandemic. There are many powerful technologies and assays…

Leica Science Lab
iPSC cells

Studying Natural Killer (NK) Cells Derived from Induced Pluripotent Stem Cells (iPSC)

The study of natural killer (NK) cells holds tremendous promise for developing novel immunotherapies. NK cells derived from induced pluripotent stem…

Leica Science Lab

Time-resolved STED microscopy

Introduced more than 30 years ago, stimulated emission depletion (STED) microscopy has raised to a standard and widely used method for imaging in the…

Leica Science Lab

Obtain maximum information from your specimen with LIGHTNING

LIGHTNING is an adaptive process for extraction of information that reveals fine structures and details, otherwise simply not visible, fully…

Leica Science Lab

Studying Adipose Tissue Development and Expansion

This article discusses sharp, high-contrast imaging of whole mount adipose (fat) tissues specimens, which are thick and round (unsectioned), with a…

Leica Science Lab

Image Gallery: THUNDER Imager

To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using…

Leica Science Lab

Infection of the novel coronavirus SARS-CoV-2 can be blocked by a human monoclonal antibody

Vaccines and targeted therapeutics for treatment of the respiratory disease COVID-19, caused by the coronavirus SARS-CoV-2, are currently lacking.…

Leica Science Lab

Expanding the frontiers of confocal live cell imaging

To address the specific challenges of live cell confocal imaging and help researchers get closer to the truth, Leica Microsystems has re-imagined…

Leica Science Lab

About Confocal

Confocal Laser Scanning Microscopy (CLSM) is one of a series of methods to generate slices from microscopic samples by means of optics. The sample stays intact, and the slicing may be repeated many times. True Confocal Scanning (TCS) is a technique, where only a single, diffraction limited spot is illuminated and observed at a time. The benefit of confocal imaging is a dramatically increased contrast by removal of out-of-focus haze. Z-sequences of optical slices (3D image stacks) are sources for subsequent rendering as anaglyphes, depth-coded maps or 3D movies. TCS is also very well compatible with multi-fluorescence imaging, time-lapse imaging, FLIMFRAP and  FCS  measurements – plus a whole world of spectral applications.

Useful Links

Communities and Web Sources

www.researchgate.net/Social network for scientists

www.lsoft.com/scripts/wl.exe?SL1=CONFOCALMICROSCOPY&H=LISTS.UMN.EDUConfocal Microscopy Mailing List, University of Minnesota

www.ibiology.org/Teaching tools, video lectures on biology and microscopy

www.ibiology.org/Teaching tools, video lectures on biology and microscopy

bitesizebio.comOnline magazine and community for molecular and cell biology researchers

www.somersault1824.comResource for high-end scientific illustrations, images and animations

Search Engines and Data Bases

www.cellimagelibrary.orgPublic resource database of images, videos, and animations of cells

harvester.fzk.de/harvesterBioinformatic meta search engine for genes and proteins

www.gopubmed.comSearch interface for pubmed

en.wikipedia.org/wiki/List_of_academic_databases_and_search_enginesList of academic databases and search engines

scholar.google.comBeta of Google's search engine for scientific article abstracts

Journals

www.doaj.org/Directory of open access journals

emboj.embopress.org/The EMBO Journal

www.lifescied.orgCBE-Life Sciences Education – an ASCB online journal

www.sciencemag.org/Science

www.nature.com/Nature

www.cell.com/Biweekly publication of exceptional research articles

jcs.biologists.org/Journal of Cell Science

dev.biologists.org/Development

jeb.biologists.org/The Journal of Experimental Biology

dmm.biologists.org/DMM Disease Models & Mechanisms

www.biotechniques.com/International Journal of Life Science Methods

www.opticsinfobase.org/Collection of Journals and Proceedings in Optics and Photonics

spie.org/x576.xmlSPIE - peer-reviewed journals on applied research in optics and photonics

onlinelibrary.wiley.com/journal/10.1002/(ISSN)1864-0648Journal of Biophotonics

www.plosone.org/home.actionInternational, peer-reviewed, open-access, online publication

rspb.royalsocietypublishing.org/Proceedings B - the Royal Society's biological research journal

www.microscopy-analysis.com/International Journal for microscopists

Organizations

www.microscopy.org/Microscopy Society of America

www.eurmicsoc.org/European Microscopy Society

www.rms.org.uk/Royal Microscopical Society

www.ascb.org/ASCB American Society of Cell Biology

www.biologists.com/cob_activities.htmlthe company of biologists

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