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PAULA, how are my cells today?

Smart Cell Imager PAULA

  • Cell Culture

    Growing cells under lab conditions is the base for scientists working in fields of cell or developmental biology, cancer research, or any kind of life science and pharma research. Find out how Leica…
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  • Live Cell Imaging

    Shifting perspective from single microscope components to a full working live cell imaging solution, Leica Microsystems integrates microscope, LAS X imaging software, cameras, and dedicated…
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  • Organoids and 3D Cell Culture

    One of the most exciting recent advancements in life science research is the development of 3D cell culture systems, such as organoids, spheroids, or organ-on-a-chip models. A 3D cell culture is an…
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  • Virology

    Do your research interests focus on viral infection and disease? Find out how you can gain insights into virology with solutions for imaging and sample preparation from Leica Microsystems.
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  • Science Lab Topic: Widefield Microscopy

    Upright Fluorescence Microscopy for Virus Replication Studies

    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread over the world quickly. Due to its dramatic impact, researchers are interested in the nature of the…
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  • Science Lab Topic: Confocal Microscopy

    Microscopy in Virology

    The coronavirus SARS-CoV-2, causing the Covid-19 disease effects our world in all aspects. Research to find immunization and treatment methods, in other words to fight this virus, gained highest…
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  • Science Lab Topic: Live-Cell Imaging

    How can PAULA help streamline the workflow for my wound healing assay?

    The wound healing assay, often used as a synonym for scratch assay or migration assay, is an important tool for the evaluation and measurement of cell migration, whether single cells or cell…
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  • MDCK cells, Phase Contrast, red outlines are marking the cell borders. Courtesy of Prof. Ralf Jacob, University of Marburg, Germany
    Science Lab Topic: Live-Cell Imaging

    Confluency Check with PAULA Cell Imager

    Many cell-based experiments require cells in a certain state. This can include their morphology,  fluorescent protein expression, and the confluency of the cell layer. Researchers check their cells…
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  • Mammalian cells can be distinguished according to their morphology. Fibroblasts (left) have a bipolar or multipolar shape. Epithelial-like cells (middle) show more regular dimensions and lymphoblast-like cells (right) are round and grow in suspension.
    Science Lab Topic: Live-Cell Imaging

    Introduction to Mammalian Cell Culture

    Mammalian cell culture is one of the basic pillars of life sciences. Without the ability to grow cells in the lab, the fast progress in disciplines like cell biology, immunology, or cancer research…
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  • Science Lab Topic: Live-Cell Imaging

    How to do a Proper Cell Culture Quick Check

    In order to successfully work with mammalian cell lines, they must be grown under controlled conditions and require their own specific growth medium. In addition, to guarantee consistency their growth…
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