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Leica DM3000 & DM3000 LED Uniquely Ergonomic System Microscopes With Intelligent Automation

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Neurons imaged with DIC contrast.

Differential Interference Contrast (DIC) Microscopy

This article demonstrates how differential interference contrast (DIC) can be actually better than brightfield illumination when using microscopy to image unstained biological specimens.
Image of MDCK (Madin-Darby canine kidney) cells taken with phase contrast.

Phase Contrast and Microscopy

This article explains phase contrast, an optical microscopy technique, which reveals fine details of unstained, transparent specimens that are difficult to see with common brightfield illumination.
Staining is crucial to revealing details in the specimens.

H&E Staining in Microscopy

If we consider the role of microscopy in pathologists’ daily routines, we often think of the diagnosis. While microscopes indeed play a crucial role at this stage of the pathology lab workflow, they…
Acute lymphoblastic leukemia

How to Benefit from Digital Cytopathology

If you have thought of digital cytopathology as characterized by the digitization of glass slides, this webinar with Dr. Alessandro Caputo from the University Hospital of Salerno, Italy will broaden…
Laboratory

Factors to consider when selecting clinical microscopes

What matters if you would like to purchase a clinical microscope? Learn how to arrive at the best buying decision from our Science Lab Article.
H&E stained specimen, 20x magnification

The Time to Diagnosis is Crucial in Clinical Pathology

Abnormalities in tissues and fluids - that’s what pathologists are looking for when they examine specimens under the microscope. What they see and deduce from their findings is highly influential, as…

Perform Microscopy Analysis for Pathology Ergonomically and Efficiently

The main performance features of a microscope which are critical for rapid, ergonomic, and precise microscopic analysis of pathology specimens are described in this article. Microscopic analysis of…
Steps of Koehler Illumination

Koehler Illumination: A Brief History and a Practical Set Up in Five Easy Steps

In this article, we will look at the history of the technique of Koehler Illumination in addition to how to adjust the components in five easy steps.

Fields of Application

Fluorescence

Find out how fluorescence microscopes from Leica Microsystems support your research. Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy for its…

Clinical Pathology

Learn how ergonomic microscopes from Leica Microsystems support accurate and timely diagnosis in clinical pathology.

Microscopy in Pathology

Analysis of specimens for pathology sometimes requires long hours working with a microscope. The result for the user may be physical discomfort and strain that can lead to reduced efficiency and the…

Anatomic Pathology

Learn how ergonomic microscopes from Leica Microsystems support efficient and accurate diagnosis in anatomic pathology.

DIC Microscopes

A DIC microscope is a widefield microscopy which has a polarization filter and Wollaston prism between the light source and condenser lens and also between the objective lens and camera sensor or…

Phase Contrast Light Microscopes

A phase contrast light microscope offers a way to view the structures of many types of biological specimens in greater contrast without the need of stains.

Darkfield Microscopes

The darkfield contrast method exploits diffraction or scattering of light from structures of a biological specimen or non-uniform features of a material sample.
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