Super-resolution microscopes and nanoscopes overcome the diffraction limit of light and allow investigators to study subcellular structures in greater detail than achieved with a standard confocal microscope. With the possibility of resolutions down to 30 nm with STED as well as sub-cellular dynamics can be studied at the nanoscale. Sub-diffraction colocalization analysis reveals interactions unprecedented detail. Enabling novel discoveries to be made in the fields of virology, immunology, neuroscience and cancer, super-resolution is on its way to becoming the new gold standard in light microscopy.
Contact a local specialist for advice on the right super-resolution or nanoscopy system for your needs.
HyVolution 2 is super-resolution for every specimen and every experiment. Study the rapid dynamics of living cells, colocalization, image multiple fluorophores simultaneously, or capture intracellular details with resolution down to 140 Nanometer.
Unlike super-resolution systems that use a single external detection channel HyVolution 2 integrates seamlessly with all confocal imaging modalities. Therefore, you can record all five channels simultaneously – without the need for sequential scanning, which would only slow down the acquisition speed.
Seamless integration with Huygens by SVI: you have the freedom to use fast parallel processing on GPU. HyVolution 2 thus becomes part of the image acquisition process making it the fastest confocal super-resolution system in every respect.
Developed with our partners from SVI.
Pulling the veil from your images: HyVolution 2 reveals minute detail in this 4-channel recording of Cos-7 cells, BodipyFL Phallacidin (Actin), Alexa Fluor 568 F(ab')2 (Tubulin), Alexa Fluor 647 F(ab')2 (Mitochondria), DAPI (nuclei). Sample courtesy of Dr. Jana Döhner, Center for Microscopy and Image Analysis, University of Zürich.
Live cell STED imaging with the new HC PL