Isabelle Köster , PhD
Isabelle Köster studied Biology at the University of Karlsruhe, where she specialized in developmental and molecular biology. She followed her interest in developmental biology with her PhD at the University Hospital of Heidelberg working on the transcriptional regulation of tissue separation in Xenopus laevis. There she developed skills in widefield, fluorescence and confocal microscopy. She has worked in a medical scientific agency before she started as scientific writer for the confocal marketing of Leica Microsystems in September 2013.
Light Sheet Microscopy Turned Vertically
Living cells and organisms often suffer from the high light intensities used for fluorescent imaging. Light sheet microscopy reduces phototoxic effects and bleaching by illuminating a specimen in only…Read article
"The Leica Digital Light Sheet Module – a Clever Example of Thinking Out of the Box"
Bram van den Broek is a postdoctoral fellow at the Netherlands cancer institute in Amsterdam where he supports the advanced microscopy techniques in the laboratory of Kees Jalink. Working with Leica…Read article
"We can go home and the imaging is done automatically by the Leica HCS A Matrix Screener."
Jutta Maria Bulkescher is the technical coordinator in the Novo Nordisk Foundation Center for Protein Research and Danish Stem Cell Center in Copenhagen, Denmark. The Leica HCS-A matrix screener is an…Read article
A Bright Dye for Live-Cell STED Microscopy
The aim of cell biology is to study smallest details on a cellular level preferably in a live cell experiment. By providing fast and direct super-resolution, STED (Stimulated Emission Depletion)…Read article
"Leica is always flexible and dynamic" - Interview with Audrey Salles, Pasteur Institute, Paris
Audrey Salles is a specialist for confocal and super-resolution microscopy at Pasteur Institute, Imagopole, PFID, Paris, France. Her research interests are cytokine signaling and skeleton organization…Read article
Deeper Insights in Transparent Animals
CLARITY clearing derivatives for multiphoton microscopy. Transparent organisms help us to identify spatial arrangements and connections of cells and tissues, especially neuronal circuits can easily…Read article
Video Interview with Stefan Hell, the Inventor of Super-Resolution
Professor Stefan Hell is director at the Max Planck Institute for Biophysical Chemistry and head of the department of NanoBiophotonics in Goettingen and widely considered as the father of…Read article
Video Interview with Timo Zimmermann
The first super-resolution image he saw was an eye opener for him: "It was not just structures that got smaller. I was looking at a sample that I specifically had high hopes of seeing another layer of…Read article
The Environment Makes the Stem Cell
A recent publication in Nature shows that all stem cells divide and compete for niche space by passively "kicking out" others so that eventually one stem cell takes over the whole niche. Jacco van…Read article
Interview with Dr. Yasushi Okada
Yasushi Okada, team leader at Riken Quantitative Biology Center in Osaka, Japan, investigates vesicular transport mechanisms in neuronal cells. As the size of transported vesicles is below 100 nm and…Read article
Tracking Glomerular Fate Over Long Time Distances
Multi-channel multiphoton microscopy with dedicated optics for CLARITY. The glomerular filtration barrier (GFB) is a complex spatial structure within the kidney glomerulis where ultrafiltration…Read article
Map the Brain with CLARITY
Imaging whole brains with CLARITY and multiphoton microscopy. Image a whole brain without sectioning? Investigate neuronal circuits without reconstruction? Perform molecular phenotyping without…Read article