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Thomas Heuser, PhD


Bibliographical sketch

  • Since 2014: Head of Electron Microscopy Facility, Campus Science Support Facilities GmbH (CSF), Vienna Biocenter, Austria
  • 2007–2014: Postdoctoral Fellowship, Brandeis University, Waltham, MA, USA
  • 2003–2006: Postdoctoral Fellowship, University of British Columbia, Vancouver, BC, Canada
  • 1999–2002: PhD Student, University of Cologne, Germany and Karlsruhe Institute of Technology, IFU, Garmisch-Partenkirchen, Germany
  • 1993–1999: Undergraduate Student, RWTH University of Aachen, Germany


Recent talks

  • 27.10.2014: Vienna, Austria: University of Vienna, Interdisciplinary Seminar Series "Light and Electron Microscopy"
  • 08.07.2013: Steamboat Springs, CO, USA: Ciliate Molecular Biology Conference of the Federation of American Societies for Experimental Biology (FASEB)
  • 08.03.2013: Tallahassee, FL, USA: Florida State University, Department of Biological Science
  • 28.06.2011: New London, NH, USA: Short Talk at Gordon Research Conference on Three Dimensional Electron Microscopy
  • 22.12.2009: Munich, Germany: Ludwig Maximilian University (LMU), Physics Department
  • 10.11.2009: La Jolla, CA, USA: The Scripps Research Institute, Workshop on EM Structure Determination of Challenging Macromolecules
  • 14.12.2008: San Francisco, CA, USA: Annual Meeting of the American Society For Cell Biology


Peer-reviewed publications

  • Bigalke JM, Heuser T, Nicastro D, and Heldwein EE: Membrane deformation and scission by the HSV-1 nuclear egress complex. Nat. Commun. 5: 4131 (2014).
  • Carbajal-González1 BI, Heuser1 T, Fu X, Lin J, Smith BW, Mitchell DR, and Nicastro D: Conserved structural motifs in the central pair complex of eukaryotic flagella. Cytoskeleton 70: 101–20 (2013).
  • Lin J, Heuser T, Song K, Fu X, and Nicastro D: One of the nine doublet microtubules of eukaryotic flagella exhibits unique and partially conserved structures. PLoS One 7 (10): e46494 (2012).
  • Heuser T, Dymek EE, Lin J, Smith EF, and Nicastro D: The CSC connects three major axonemal complexes involved in dynein regulation. Mol. Biol. Cell 23: 3143–55 (2012).
  • Heuser1 T, Barber1 CF, Lin J, Krell J, Rebesco M, Porter ME, and Nicastro D: Cryo-electron tomography reveals doublet specific structures and unique interactions in the I1 dynein. Proc. Natl. Acad. Sci. USA 109: E2067–76 (2012).
  • Barber1 CF, Heuser1 T, Carbajal-González BI, Botchkarev VV Jr, and Nicastro D: Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella. Mol. Biol. Cell 23: 111–20 (2012).
  • Lin J, Heuser T, Carbajal-González BI, Song K, and Nicastro D: The structural heterogeneity of radial spokes in cilia and flagella is conserved. Cytoskeleton 69: 88–100 (2012).
  • Nicastro D, Fu X, Heuser T, Tso A, Porter ME, and Linck RW: Cryo-electron tomography reveals conserved features of doublet microtubules in flagella. Proc. Natl. Acad. Sci. USA 108: E845–53 (2011).
  • Dymek EE, Heuser T, Nicastro D, and Smith EF: The CSC is required for complete radial spoke assembly and wild-type ciliary motility. Mol. Biol. Cell 22: 2520–31 (2011).
  • Heuser T, Raytchev M, Krell J, Porter ME, and Nicastro D: The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella. J. Cell Biol. 187: 921–33 (2009).
  • van der Geize R, Yam K, Heuser T, Wilbrink MH, Hara H, Anderton MC, Sim E, Dijkhuizen L, Davies JE, Mohn WW, and Eltis LD: A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. Proc. Natl. Acad. Sci. USA 104: 1947–52 (2007).
  • Heuser T, and Zimmer W: Genus- and isolate-specific real-time PCR quantification of Erwinia on leaf surfaces of English oaks (Quercus robur L). Current Microbiol. 47: 214–19 (2003).
  • Heuser T, and Zimmer W: Quantitative analysis of phytopathogenic ascomycota on leaves of pedunculate oaks (Quercus robur L) by real-time PCR. FEMS Microbiol. Letters 209: 295–99 (2002).
  • Miller B, Heuser T, and Zimmer W: Functional involvement of a Deoxy-D-xylulose 5-phosphate reductoisomerase gene harboring locus of Synechococcus leopoliensis in isoprenoid biosynthesis. FEBS Letters 481: 221–26 (2000).
  • Miller B, Heuser T, and Zimmer W: A Synechococcus leopoliensis SAUG 1402-1 Operon harboring the 1-deoxyxylulose 5-phosphate Synthase Gene and two additional Open Reading Frames is functionally involved in the Dimethylallyl Diphosphate Synthesis. FEBS Letters 460: 485–90 (1999).

1: shared first authorship