Contact & Support
Header Image

Narendra Jha


Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400 076, India

  • Effect of curcumin analogs onα-synuclein aggregation and cytotoxicity

    Alpha-synuclein (α-Syn) aggregation into oligomers and fibrils is associated with dopaminergic neuron loss occurring in Parkinson’s disease (PD) pathogenesis. Compounds that modulate α-Syn aggregation and interact with preformed fibrils/oligomers and convert them to less toxic species could have promising applications in the drug development efforts against PD. Curcumin is one of the Asian food ingredient which showed promising role as therapeutic agent against many neurological disorders including PD.
    Read article