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Jürgen J. Schmied, PhD


Jürgen Schmied studied Biophysics at the University of Bayreuth and graduated in 2010. During his PhD thesis he worked on DNA origami based fluorescence standards which allow to test the spatial resolution of super-resolution microscopes such as STED or GSDIM. After finishing his thesis he founded a company (GATTAquant GmbH) which commercializes DNA origami based standards for any type of fluorescence microscope but also for TEM and AFM.

  • From 2004–2010: Studies Physics (Biophysics), University Bayreuth, Germany
  • From 2007–2008: Studies Physics, ENS-Lyon, France
  • From 2010–2014: PhD thesis at the Technische Universität Braunschweig, Germany (Prof. Dr. Philip Tinnefeld): "Applications of Fluorescently Labeled DNA Origami Structures"
  • From 2014 CEO of GATTAquant GmbH, Braunschweig, Germany. GATTAquant developes and offers fluorescent standards based on the DNA Origami technique.
  • Measuring the 3D STED-PSF with a new Type of Fluorescent Beads

    A new type of fluorescent bead is presented by GATTAquant. These beads, called GATTA-Beads, are characterized by a small diameter (23 nm), high intensity and size uniformity. In combination with state-of the-art STED microscopes such as the Leica TCS SP8 STED 3X and high-end image restoration methods available in the Huygens Software, it is shown that these new beads can be used for accurate STED PSF characterization in 3D. Furthermore, it is shown that the measured 3D STED-PSF can be used to improve image restoration quality in combination with STED deconvolution methods available in the Huygens Software.
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  • Quantifying the Resolution of a Leica SR GSD 3D Localization Microscopy System with 2D and 3D Nanorulers

    DNA origami based nanorulers produced by GATTAquant are common standards to test the achievable spatial resolution of super-resolution microscopes. Recently the nanorulers were used to test the performance of the Leica SR GSD 3D microscope.
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  • Abstracts of the 5th European Super-Resolution User-Club Meeting

    The 5th Super-Resolution User Club Meeting was held in collaboration with Professor Kees Jalink and The Netherlands Cancer Institute (NKI) in Amsterdam. Having the meeting at a location where super-resolution microscopy is used on a daily basis makes a big difference, offering participants the chance to use live cells for workshops and see systems working in their true environments. Thanks also to the scientists that supported the meeting by coming and giving talks. As super-resolution continues to grow in importance in research, we recognize the need to come together to network, share information and experiences. Here we present the abstracts of the talks.
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