Pumaree Kanrai , Dr. rer. nat.

Pumaree Kanrai studied Virology and Biology and Biochemistry at the Justus Liebig University Giessen in Giessen. She had more than 10 years of experience in Infectious diseases as well as Virus vaccine development. In her dissertation at the Justus Liebig University Giessen she examined the Genetic diversity and host adaptation of avian H5N1 influenza viruses during human infection. In January 2017 she joined the Max Planck Institute for Heart and Lung Research and is responsible to planned and executed the project related to lung repair and regeneration after Virus infection. She used an organoids 3D cell culture examined the self-organizing structures formed by adult tissue stem cells or pluripotent stem cells. Moreover, she empower of an Organoids culture to recapitulate cell-cell interaction, cell-niche interactions in tissue development, homeostasis, regeneration and disease, and provide an in vitro model for drug screening.

Lung organoid taken at the "liquid-air interface" with a THUNDER Imager 3D Cell Culture. The cells originate from transgenic mice, so that the different fluorescence represents the degree of differentiation of the respective cell (superposition). The image acquisition was performed on day 21 after the start of the culture. Reference: P. Kanrai, MPI-HLR Bad Nauheim.

Observing 3D Cell Cultures During Development

3D cell cultures, such as organoids and spheroids, give insights into cells and their interactions with their microenvironment. These 3D cell cultures are playing an increasingly important role for…