Image Gallery: Application Options with Leica DM2500 LED Microscope

Trachea in higher magnification (20x) H&E staining, brightfield. Trachea.Brightfield_20x_dry_.jpg

The number of applications in microscopy can be as manifold as life itself. Different specimens demand different <link science-lab optical-contrast-methods>contrast methods to get a decent result. Unstained cells normally do not show a very high contrast. Researchers approach this problem by either staining the specimen with dyes respectively fluorescent molecules; or adding contrast by manipulating the light passing through.

The Leica DM2500 LED offers the above mentioned contrasting methods to meet each specimen’s demands:

  • brightfield for stained histological sections
  • <link science-lab phase-contrast>phase contrast to image unstained cells
  • <link science-lab differential-interference-contrast-dic>differential interference contrast (DIC) for unstained samples and a relief-like view
  • <link science-lab polarization-contrast>polarization contrast to watch crystals or e.g. cellulose
  • <link science-lab an-introduction-to-fluorescence>fluorescence to visualize dedicated cellular components by immunofluorescence

Especially in the clinical sector, a clear differentiation of colours in the sample is necessary, when analysing stained specimen in brightfield. Here the LED illumination of the Leica DM2500 LED can help the user to make clear decisions.

This image gallery shows examples from life science and clinical applications using the Leica DM2500 LED microscope. 

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