How to Conduct Localized Proteomics of Microscopic Regions

This webinar is about a recently developed technique that allows localized proteomics of microscopic regions of interest, such as specific cell types or neuropathological features of disease.

This technique uses laser capture microdissection (LCM) to isolate regions/cells of interest followed by label-free quantitative mass spectrometry (LC-MS) and has been optimized to use formalin-fixed paraffin embedded (FFPE) tissue, so that archived human tissue specimens can be used. This is a particular advantage, as the vast majority of human tissue specimens are FFPE blocks, which are currently an underutilized, but exceptionally valuable resource for medical research.

• Scientists working in proteomics
• Scientists working with FFPE tissues
• Scientists looking at molecular mechanisms in disease (especially Alzheimer)
• Scientists interested in Laser Microdissection