Over the last years, Optical Coherence Tomography (OCT) has become a potential real-time surgical assistive device. Numerous vitreoretinal surgical conditions have been described in the literature, including macular holes, epiretinal membranes, retinal detachments, vitreomacular traction, and retinopathy of prematurity. The high-resolution, cross sectional information provided by iOCT creates a unique feedback system for vitreoretinal surgery. Tissue planes, architectural alterations, and residual membranes can all be visualized utilizing iOCT.
The PIONEER Study conducted by the Cole Eye Institute is a three-year exploratory study to investigate clinical feasibility, the impact on surgical decision-making, and the potential safety of a microscope-mounted portable iOCT. PIONEER represents the largest study to date examining the feasibility, utility, and safety of iOCT.