DNA Research
Ran R, Li L, Shi Z, Liu G, Jiang H, Fang L, Xu T, Huang J, Chen W, Chen Y:
Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis
Molecular Oncology, 06 Aug 2022, doi:10.1111/mol2.13301
Gniadecki R, Iyer A, Hennessey D, Khan L, O'Keefe S, Redmond D, Storek J, Durand C, Cohen-Tervaert JW, Osman M:
Genomic instability in early systemic sclerosis
J Autoimmun. 2022 Jul 6;131:102847. doi: 10.1016/j.jaut.2022.102847.
Lee BCH, Robinson PS, Coorens THH, Yan HHN, Olafsson S, Lee-Six H, Sanders MA, Siu HC, Hewinson J, Yue SSK, Tsui WY, Chan ASY, Chan AKW, Ho SL, Campbell PJ, Martincorena I, Buczacki SJA, Yuen ST, Leung SY, Stratton MR:
Mutational landscape of normal epithelial cells in Lynch Syndrome patients
Nat Commun. 2022 May 17;13(1):2710. doi: 10.1038/s41467-022-29920-2.
RNA Research
Friedrich SR, Nevue AA, Andrade ALP, Velho TAF, Mello CV:
Emergence of sex-specific transcriptomes in a sexually dimorphic brain nucleus
Cell Rep. 2022 Aug 2;40(5):111152. doi: 10.1016/j.celrep.2022.111152.
Ito N, Takatsu A, Ito H, Koike Y, Yoshioka K, Kamei Y, Imai SI:
Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
Cell Rep. 2022 Jul 26;40(4):111131. doi: 10.1016/j.celrep.2022.111131.
Sun X, Xiong H, Jiang C, Zhang D, Yang Z, Huang Y, Zhu W, Ma S, Duan J, Wang X, Liu W, Guo H, Li G, Qi J, Liang C, Zhang Z, Li J, Zhang H, Han L, Zhou Y, Peng Y, Li Z.:
Natural variation of DROT1 confers drought adaptation in upland rice
Nat Commun. 2022 Jul 23;13(1):4265. doi: 10.1038/s41467-022-31844-w.
Proteomics, Lipidomics, Metabolomics
Strack R.:
Spatial proteomics with subcellular resolution
Nat Methods. 2022. PMID: 35804240
Mund A, Brunner AD, Mann M:
Unbiased spatial proteomics with single-cell resolution in tissues
Mol Cell. 2022 Jun 16;82(12):2335-2349. doi: 10.1016/j.molcel.2022.05.022.
Mitchell, D., Hunt, A. L., Conrads, K. A., Hood, B. L., Makohon-Moore, S. C., Rojas, C., Maxwell, G. L., Bateman, N. W., Conrads, T. P.:
Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment
J. Vis. Exp. (184), e64171, doi:10.3791/64171 (2022).
Fluorescence Applications
Leitner DF, Kanshin E, Askenazi M, Faustin A, Friedman D, Devore S, Ueberheide B, Wisniewski T, Devinsky O:
Raphe and ventrolateral medulla proteomics in epilepsy and sudden unexpected death in epilepsy
Brain Communications, fcac186
Dzamukova M, Brunner TM, Miotla-Zarebska J, Heinrich F, Brylka L, Mashreghi MF, Kusumbe A, Kühn R, Schinke T, Vincent TL, Löhning M:
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth
Nat Commun. 2022 Jun 1;13(1):3059. doi: 10.1038/s41467-022-30618-8.
Oh H, Newton D, Lewis D, Sibille E:
Lower Levels of GABAergic Function Markers in Corticotropin-Releasing Hormone-Expressing Neurons in the sgACC of Human Subjects With Depression
Front Psychiatry. 2022 Feb 25;13:827972. doi: 10.3389/fpsyt.2022.827972. eCollection 2022.
Cancer Research
Ran R, Li L, Shi Z, Liu G, Jiang H, Fang L, Xu T, Huang J, Chen W, Chen Y:
Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis
Molecular Oncology, 06 Aug 2022, doi:10.1111/mol2.13301
Prieto-Vila M, UsubaW, Yoshioka Y, Takeshita F, Yoshiike M, Sasaki H, Yamamoto Y, Kikuchi E, Ochiya T:
High-grade bladder cancer cells secrete extracellular vesicles containing miRNA-a-p and promotes angiogenesis
J of Extracellular Bio. 2022;1:e47. DOI: 10.1002/jex2.47
Comba A, Faisal SM, Dunn PJ, Argento AE, Hollon TC, Al-Holou WN, Varela ML, Zamler DB, Quass GL, Apostolides PF, Abel C 2nd, Brown CE, Kish PE, Kahana A, Kleer CG, Motsch S, Castro MG, Lowenstein PR:
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
Nat Commun. 2022 Jun 24;13(1):3606. doi: 10.1038/s41467-022-31340-1.
Neurosciences
Friedrich SR, Nevue AA, Andrade ALP, Velho TAF, Mello CV:
Emergence of sex-specific transcriptomes in a sexually dimorphic brain nucleus
Cell Rep. 2022 Aug 2;40(5):111152. doi: 10.1016/j.celrep.2022.111152.
Yamaguchi Y, Murai I, Takeda M, Doi S, Seta T, Hanada R, Kangawa K, Okamura H, Miyake T, Doi M:
Nmu/Nms/Gpr176 Triple-Deficient Mice Show Enhanced Light-Resetting of Circadian Locomotor Activity
Biol Pharm Bull. 2022;45(8):1172-1179. doi: 10.1248/bpb.b22-00260.
Leitner DF, Kanshin E, Askenazi M, Faustin A, Friedman D, Devore S, Ueberheide B, Wisniewski T, Devinsky O:
Raphe and ventrolateral medulla proteomics in epilepsy and sudden unexpected death in epilepsy
Brain Communications, fcac186
Clinical/Pathology/Immunology Research Applications
Miyake Y, Obana M, Yamamoto A, Noda S, Tanaka K, Sakai H, Tatsumoto N, Makino C, Kanemoto S, Shioi G, Tanaka S, Maeda M, Okada Y, Imaizumi K, Asanuma K, Fujio Y:
Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis
Commun Biol. 2022 Jul 22;5(1):734. doi: 10.1038/s42003-022-03709-x.
Tsujihana K, Tanegashima K, Santo Y, Yamada H, Akazawa S, Nakao R, Tominaga K, Saito R, Nishito Y, Hata RI, Nakamura T, Murai I, Kono Y, Sugawa M, Tanioka M, Egawa G, Doi M, Isa T, Kabashima K, Hara T, Okamura H:
Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity
Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2116027119. doi: 10.1073/pnas.2116027119. Epub 2022 Jun 15.
Zwiers PJ, Jongman RM, Kuiper T, Moser J, Stan RV, Göthert JR, van Meurs M, Popa ER, Molema G:
Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice
PLoS One. 2022 Jun 8;17(6):e0268986. doi: 10.1371/journal.pone.0268986. eCollection 2022.
Developmental Research, Epigenetics & Aging
Ito N, Takatsu A, Ito H, Koike Y, Yoshioka K, Kamei Y, Imai SI:
Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
Cell Rep. 2022 Jul 26;40(4):111131. doi: 10.1016/j.celrep.2022.111131.
Dzamukova M, Brunner TM, Miotla-Zarebska J, Heinrich F, Brylka L, Mashreghi MF, Kusumbe A, Kühn R, Schinke T, Vincent TL, Löhning M:
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth
Nat Commun. 2022 Jun 1;13(1):3059. doi: 10.1038/s41467-022-30618-8.
Gorman LM, Konciute MK, Cui G, Oakley CA, Grossman AR, Weis VM, Aranda M, and Davy SK:
Symbiosis with Dinoflagellates Alters Cnidarian Cell-Cycle Gene Expression
Cellular Microbiology, (23rd May) Volume 2022, Article ID 3330160, 20 pages
Plant Research
Wu H, Li G, Zhan J, Zhang S, Beall BD, Yadegari R, Becraft PW:
Rearrangement with the nkd2 promoter contributed to allelic diversity of the r1 gene in maize (Zea mays)
Plant J. 2022 Jul 25. doi: 10.1111/tpj.15918.
Sun X, Xiong H, Jiang C, Zhang D, Yang Z, Huang Y, Zhu W, Ma S, Duan J, Wang X, Liu W, Guo H, Li G, Qi J, Liang C, Zhang Z, Li J, Zhang H, Han L, Zhou Y, Peng Y, Li Z.:
Natural variation of DROT1 confers drought adaptation in upland rice
Nat Commun. 2022 Jul 23;13(1):4265. doi: 10.1038/s41467-022-31844-w.
Balestrini R, Sillo F:
Plant-Fungal Interactions: Laser Microdissection as a Tool to Study Cell Specificity
Methods Mol Biol. 2022;2536:369-380. doi: 10.1007/978-1-0716-2517-0_20.
Forensics
Rhodes C:
Population Genetic Issues for Forensic DNA Profiles
NCJRS, Document Number: 304612, Date Received: April 2022, Award Number: 2017-DN-BX-0136
Sun M, Zheng J, Wnag B and Yao J:
Sperm Cell Capture Based on ABH Antigen Differences to Separate Two Men in Mixed Seminal Stains
BioMed Research International, Volume 2021 | Article ID 7269237
Prajapati S, Rajmane P, Jayakrishna P, Nair MS, Kshirsagar P and Meshram M:
Application and utility of alternative methods in isolation of pure cells from forensic biological mixtures in modern-day: a review
JFSR – Journal of Forensic Science and Research, Aug 2021, ISSN 2575-0186
General Information:
http://projects.nfstc.org/tech_transition/lmd/examiners/
Further information on Leica LMD impact at forensics:
http://www.fox23.com/news/news/local/new-dna-lab-brings-hope-victims-families/nj97Z/
Miscellaneous
Liu Y, Chen L, Yu J, Ye L, Hu H, Wang J, Wu B:
Advances in Single-Cell Toxicogenomics in Environmental Toxicology
Environ Sci Technol. 2022 Jul 26. doi: 10.1021/acs.est.2c01098.
Acland, M.; Mittal, P.; Arentz, G.; Whitehead, F.; Hoffmann, P.; Klingler-Hoffmann, M.; Oehler, M.K. A:
Protocol for the Acquisition of Comprehensive Proteomics Data from Single Cases Using Formalin-Fixed Paraffin Embedded Sections
Methods Protoc. 2022, 5, 57.
Mitchell, D., Hunt, A. L., Conrads, K. A., Hood, B. L., Makohon-Moore, S. C., Rojas, C., Maxwell, G. L., Bateman, N. W., Conrads, T. P.:
Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment
J. Vis. Exp. (184), e64171, doi:10.3791/64171 (2022).
Live Cell Culture
Gao F, Zhang G, Liu Y, He Y, Sheng Y, Sun X, Du Y, Yang C:
Activation of CD44 signaling in leader cells induced by tumor-associated macrophages drives collective detachment in luminal breast carcinomas
Cell Death Dis. 2022 Jun 9;13(6):540. doi: 10.1038/s41419-022-04986-4.
Zhang B, Su W, Hu J, Xu J, Askar P, Bao S, Zhou S, Chen G, Gu Y:
Transcriptome Analysis of Schwann Cells at Various Stages of Myelination Implicates Chromatin Regulator Sin3A in Control of Myelination Identity
Neurosci Bull. 2022 Apr 10. doi: 10.1007/s12264-022-00850-9.
Chen Y, Jiang H, Xiong J, Shang J, Chen Z, Wu A, Wang H:
Insight into the Molecular Characteristics of Langhans Giant Cell by Combination of Laser Capture Microdissection and RNA Sequencing
Journal of Inflammation Research, 2 Feb 2022, Vol. 15, doi: 10.2147/JIR.S337241
