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Novel Microscopy-Based Screening Method Reveals Regulators of Contact-Dependent Intercellular Transfer

Microscopy in the context of biomedical research is demanding new tools to automatically detect and capture objects of interest. The few extant packages addressing this need, however, have enjoyed limited uptake due to complexity of use and installation. To overcome these drawbacks, we developed iMSRC, which combines ease of use and installation with high flexibility and enables applications such as rare event detection and high-resolution tissue sample screening, saving time and resources.

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Frei DM, Hodneland E, Rios-Mondragon I, Burtey A, Neumann B, Bulkescher J, Schölermann J, Pepperkok R, Gerdes HH, Kögel T

Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer

Scientific Reports 5: 12879 (2015); doi:10.1038/srep12879