Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

Latest Articles

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Golgi organizational changes in response to cell stress
In this episode of MicaCam, our special guest George Galea from EMBL Heidelberg will look at HeLa Kyoto cells treated with various chemotherapeutic…
Jun 20, 2022
Webinar
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Cardiomyocyte Proliferation Upon Heart Injury in Zebrafish
This edition of MicaCam focuses on the study of the zebrafish (Danio rerio) whose heart cells can fully regenerate after injury.
Jun 09, 2022
Webinar
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Download Multiplexed Imaging Glossary
Human tissues contain a many different biomarkers which can be explored to reveal the workings of biological pathways and interrogate disease states.…
Jun 08, 2022
Story
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Hydraulics in the Automotive and Aerospace Industries
Cleanliness standards relating to lubricants, hydraulic fluids, and oils, e.g., ISO 4406 and DIN 51455 are discussed in this article. Cleanliness…
Jun 08, 2022
Story
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TauInteraction – Studying Molecular Interactions with TauSense
Fluorescence microscopy constitutes one of the pillars in life sciences and is a tool commonly used to unveil cellular structure and function. A key…
Jun 07, 2022
Story
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Studying Wound Healing of Smooth Muscle Cells
This article discusses how wound healing of cultured smooth muscle cells (SMCs) in multiwell plates can be reliably studied over time with less effort…
Jun 07, 2022
Case Study
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AI-Enabled Spatial Analysis of Complex 3D Datasets
Coming next on MicaCam - Livestream on 15th June 2022
Jun 03, 2022
Webinar
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Cleanliness of Automotive Components and Parts
This article discusses the ISO 16232 standard and VDA 19 guidelines and briefly summarizes the particle analysis methods. They give important criteria…
Jun 02, 2022
Story
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How Does The Cytoskeleton Transport Molecules?
See how 3D cysts derived from MDCK cells help scientists understand how proteins are transported and recycled in tissues and the role of the…
Jun 01, 2022
Webinar
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Fast, High Acuity Imaging and AI-assisted Analysis
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample…
Jun 01, 2022
Whitepaper
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Improving the Cleanliness Analysis Workflow
For automotive manufacturers and automotive component suppliers, obtaining cleanliness results rapidly, accurately, and reliably over the entire…
May 31, 2022
Workflow
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Studying Early Phase Development of Zebrafish Embryos
This second edition of MicaCam focuses on combining widefield and confocal imaging to study the early-stage development of zebrafish embryos (Danio…
May 25, 2022
Webinar
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Tumor MHC Expression and Intralesional IL2 Response in Melanoma
Genomics profiling and Cell DIVE multiplex imaging allows researchers to understand the immune cell phenotypes that most strongly predict response to…
May 19, 2022
Abstract
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How AR Helps in the Surgical Treatment of Moyamoya Disease
Moyamoya disease is a rare chronic occlusive cerebrovascular disorder characterized by progressive stenosis in the terminal portion of the internal…
May 19, 2022
Case Study
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Multi-Color Caspase 3/7 Assays with Mica
Caspases are involved in apoptosis and can be utilized to determine if cells are undergoing this programmed cell death pathway in so-called caspase…
May 10, 2022
Tutorial
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How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation
The first edition of MicaCam focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example…
Apr 27, 2022
Webinar
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Wt1 Genes Can Induce a Cardiomyocyte to Epicardial-like Cell Fate Transition
From this study, it was concluded that Wt1 plays a yet undescribed role for cardiomyocyte differentiation by repressing chromatin opening at specific…
Apr 27, 2022
Abstract
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Gentle 3D Imaging of Biological Samples
For 3D imaging of biological samples, light sheet microscopy is a powerful and sensitive tool allowing you to measure (sub)cellular dynamics over long…
Apr 20, 2022
Story