The Microscopy Knowledge Portal

This article explains how to avoid the phenomen of "empty magnification" in microscopy.

An exquisite beverage deserves a high-quality glass. Even the ancient Romans made artistically crafted drinking glasses. In the Middle Ages, Venetian…

A study carried out jointly by Leica Microsystems and the Institute of Neuroinformatics at the University of Zurich and Swiss Federal Institute of…

This study evaluated the effect of an occupational therapy ergonomics intervention on the workstation design and body positioning of microscope…

Using TIRF microscopy, scientists have been able to take a closer look at intracellular transport processes with the example of the galactose-binding…

For the study of minute marine organisms such as free swimming larvae or bottom dwelling invertebrates it is a great advantage to have modern…

Artificial illumination can harm hypogean monuments by inducing the uncontrolled growth of photosynthetic biofilms (green sickness or maladie verte).…

In recent years light microscopy studies have been dominated by live cell imaging while electron microscopy has been used for high-resolution studies.…

Until the middle of the 19th century, microscopes were hand-crafted custom instruments. At the time, it was not possible to predict the properties of…

For millennia, glass was admired for its beauty and the artful objects that could be created with it. With the rise of the exact sciences, however,…

The 17th century in Europe was marked by the Thirty Years' War (1618–1648). The population lived in constant fear and poverty. Marauding hordes…

We report about two-photon activation of a photoactivatable derivative of the Aequorea Victoria green fluorescent protein (pa-GFP). This special form…

Förster Resonance Energy Transfer (FRET) is a technique, which allows insight into the interactions between proteins or molecules in proximities…

Advanced microscopical techique for life science: multiphoton microscopy. Multi-photon excitation (MPE) microscopy plays a growing role among…

Among all photobleaching experiments which have been described, fluorescence recovery after photobleaching (FRAP) is the most popular. It employs…

Fluorescence is a process where a substance after having absorbed light (photons) emitts a radiation the wavelength (colour) of which is longer than…