The Microscopy Knowledge Portal
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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Topics – A Vast Amount of Expert Knowledge
- Basics in Microscopy
- Confocal Microscopy
- Digital Microscopy
- Dentistry
- EM Sample Preparation
- Fluorescence Microscopy
- Light Sheet Microscopy
- Neurosurgery
- Optical Coherence Tomography
- Super-Resolution
- Stereo Microscopy
- Surface Metrology
- Quality Assurance
- Otolaryngology (ENT)
- Ophthalmology
- Plastic Reconstructive
- Widefield Microscopy
- More
Latest Articles
Augmented Reality and Fluorescence: Clinical Uses in Cerebrovascular and Skull Base Neurosurgery
In this webinar Dr. Bendok and Dr. Morcos explain how Augmented Reality and Fluorescence can enhance visualization and support surgical decision making. They present first-hand experience of the GLOW…Read article
Getting Sharper 3D Images of Thick Biological Specimens with Widefield Microscopy
Widefield fluorescence microscopy is often used to visualize structures in life science specimens and obtain useful information. With the use of fluorescent proteins or dyes, discrete specimen…Read article
What is intraoperative OCT telling us?
In the following videos are excerpts taken from a webinar delivered by Dr. Barbara Parolini. During the webinar Dr. Parolini discusses and illustrates how intraoperative OCT provides real-time,…Read article
From dentistry to micro-dentistry: See more – optimize your dental workflow
Endodontics expert Fabio Gorni shares his vast experience in micro-dentistry and provides answers to questions of the webinar participants at the end of the recording. This webinar allows you to…Read article
Industrial Microscopy: Digital imaging and the Leica DVM6
This webinar will discuss digital microscopy and Leica’s digital DVM6 microscope. We will navigate the difference between optical and digital magnification, explain the differences in optics, and…Read article
Reasons Why There is Growing Need for Fast and Reliable Steel Quality Rating Solutions
Steel quality is critical for the manufacturing of high-quality components and products. Fast, reliable, and accurate detection and classification of inclusions has become essential for both component…Read article
The Benefits of Fluorescein and ICG use in Vascular Neurosurgery
In this webinar Professor Marco Cenzato, head of neurosurgery in the Niguarda Hospital in Milan, Italy talks about the use of Fluorescein Sodium and Indocyanine Green (ICG) in Vascular Neurosurgery.Read article
Inverted Microscopes for Grain Size Analysis: Three Factors to Consider
Microscopic steel grain size analysis is useful in determining the quality of steel alloys for a given purpose such as building bridges vs railroad rails. This webinar will describe the preparation of…Read article
Optimized Vision in Endodontic Surgeries and Procedures
Microscopes are playing an increasingly important role in endodontic surgery as they enable minimally invasive procedures to be carried out. Endodontists can work with high precision from the first…Read article
Crystal clear cryo light-microscopy images
This article describes how computational clearing of cryo light microscopy images improves the identification of cellular targets for cryo electron-microscopy.Read article
Depth Profiling and Layer Analysis for Inspection of Materials with a 2-In-1 Solution Combining Optical Microscopy and Laser Spectroscopy
In addition to simultaneous visual and chemical inspection, a 2-methods-in-1 materials analysis solution, which combines optical microscopy and laser induced breakdown spectroscopy (LIBS), can also be…Read article
Microscopy in Virology
The coronavirus SARS-CoV-2, causing the Covid-19 disease effects our world in all aspects. Research to find immunization and treatment methods, in other words to fight this virus, gained highest…Read article
IL-18 cytokine derived from the enteric nervous system is important for intestinal immunity
Interleukin 18 (IL-18) is a proinflammatory cytokine, which induces cell-mediated immune reaction upon bacterial infection. In the intestine, it is known that IL-18 is produced in immune and…Read article
Surgical Microscopes: Key Factors for OR Nurses
Operating room (OR) nurses are vital to the surgery process. An OR Nurse Manager explains the key surgical microscope features to facilitate their work.Read article
Observing the effect on transcription factor signaling and chromatin landscapes in cells infected with the human coronavirus 229E
Viral infection triggers an inflammatory cellular response which is characterized by altered gene expression. In this study, the influence of coronaviruses on cellular NF-κB (transcription factor)…Read article
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