Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

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How FRET/FLIM Biosensors and Lifetime Imaging Helped Identify the Importance of Zinc for Human B-Cell Development
In her latest studies, Dr. Mukta Deobagkar-Lele investigated the role of ZIP7, a zinc transporter protein, in modulating B cell activity and its…
Jul 30, 2019
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Researchers use Functional Imaging to Elucidate the Role of Cellular Zn²⁺ in Human Immunity
An international consortium of researchers has found a new mutation in a gene harboring a reticulum-to-cytoplasm zinc transporter. The gene is called…
Feb 27, 2019
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Role of circadian gene Clock during differentiation of mouse pluripotent stem cells
Biological rhythms controlled by the circadian clock are absent in embryonic stem cells (ESCs). However, they start to develop during the…
Mar 14, 2018
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Video: Genome Engineering with CRISPR-Cas9
Jennifer Doudna tells the story of how studying the way bacteria fight viral infection turned into a genomic engineering technology that has…
Jun 09, 2017
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Video: Genome Editing with CRISPR-Cas9
This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including…
Jun 08, 2017
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Five Big Mysteries about CRISPR’s Origins
Francisco Mojica was not the first to see CRISPR, but he was probably the first to be smitten by it. He remembers the day in 1992 when he got his…
Feb 20, 2017
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Human NK Cell Development Requires CD56-mediated Motility and Formation of the Developmental Synapse
While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are…
Feb 15, 2017
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Gene Editing with CRISPR/Cas9 - Breakthrough in Genome Engineering
The CRISPR/Cas9 system is one of several different bacterial systems for defense against viral attacks. It consists of two main components. One is a…
Nov 17, 2016
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Latest Articles

How FRET/FLIM Biosensors and Lifetime Imaging Helped Identify the Importance of Zinc for Human B-Cell Development

Researchers use Functional Imaging to Elucidate the Role of Cellular Zn²⁺ in Human Immunity

Role of circadian gene Clock during differentiation of mouse pluripotent stem cells

Video: Genome Engineering with CRISPR-Cas9

Video: Genome Editing with CRISPR-Cas9

Five Big Mysteries about CRISPR’s Origins

Human NK Cell Development Requires CD56-mediated Motility and Formation of the Developmental Synapse

Gene Editing with CRISPR/Cas9 - Breakthrough in Genome Engineering