Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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AI-Enabled Spatial Analysis of Complex 3D Datasets
VIDEO ON DEMAND - This edition of MicaCam offers practical advice on the extraction of publication grade insights from microscopy images. Our special guest Luciano Lucas (Leica Microsystems) will…
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How To Perform Fast & Stable Multicolor Live-Cell Imaging
With the help of live-cell imaging researchers gain insights into dynamic processes of living cells up to whole organisms. This includes intracellular as well as intercellular activities. Protein or…
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Imaging of Cardiac Tissue Regeneration in Zebrafish
Learn how to image cardiac tissue regeneration in zebrafish focusing on cell proliferation and response during recovery. MicaCam Episode 04 with Laura Peces-Barba Castaño from the Max Planck…
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How Does The Cytoskeleton Transport Molecules?
VIDEO ON DEMAND - See how 3D cysts derived from MDCK cells help scientists understand how proteins are transported and recycled in tissues and the role of the cytoskeleton in this transport.
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Studying Early Phase Development of Zebrafish Embryos
VIDEO ON DEMAND - This second edition of MicaCam focuses on combining widefield and confocal imaging to study the early-stage development of zebrafish embryos (Danio rerio), from oocyte to…
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How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation
VIDEO ON DEMAND - The first edition of MicaCam focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example of studying the mitochondrial…
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Wt1 Genes Can Induce a Cardiomyocyte to Epicardial-like Cell Fate Transition
From this study, it was concluded that Wt1 plays a yet undescribed role for cardiomyocyte differentiation by repressing chromatin opening at specific genomic loci and that sustained ectopic expression…
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The Potential of Coherent Raman Scattering Microscopy at a Glance
Coherent Raman scattering microscopy (CRS) is a powerful approach for label-free, chemically specific imaging. It is based on the characteristic intrinsic vibrational contrast of molecules in the…
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A Versatile Palette of Fluorescent Probes
Researchers at the Max Planck Institute for Medical Research in Heidelberg have developed a general strategy to synthesize live-cell compatible fluorogenic probes, and the result are the new MaP (Max…