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Gates Open for Improved Confocal Fluorescence and Super-Resolution STED
True confocal microscope systems feature single-point illumination and single-point detection. The method is called "optical sectioning" since the…
Jan 23, 2013Tutorial -
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Mitochondrial DNA Molecules are Packaged Individually
At the Max Planck Institute for Biology of Ageing in Cologne founded in 2008, three departments are working on the molecular, physiological and…
Jan 06, 2013Story -
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Abstracts of the 2nd European Super-Resolution User-Club Meeting
The 2nd meeting of the Leica Super-resolution User club was held from September 25 to 27, 2012 in collaboration with the Science for Life Laboratory…
Nov 01, 2012Story -
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Visualization of the Natural Killer Cell Immune Synapse by Super-Resolution Nanoscopy
Natural killer (NK) cells are innate immune effectors that recognize and kill virally infected and tumorigenic cells. Central to their effector…
Mar 08, 2012Story -
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Sharp Live Images from the Mouse Brain
To explore the most intricate structures of the brain in order to decipher how it functions – Stefan Hell’s team of researchers at the Max Planck…
Mar 04, 2012Abstract -
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Dual Channel STED Nanoscopy of Lytic Granules on Actin Filaments in Natural Killer Cells
Natural killer (NK) cells are innate immune effectors that eliminate diseased and tumorigenic targets through the directed secretion of specialized…
Mar 01, 2012Abstract -
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Videos on STED Microscopy and its Inventor Stefan Hell
Here we present an collection of videos telling the story of the invention of nanometer-scale microscopy by Stefan Hell and explaining the basic…
Dec 08, 2011Tutorial -
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Subcellular Localization of AKT and Tubulin using Super-Resolution Microscopy
Stimulated Emission Depletion microscopy, or STED nanoscopy, is a technique that uses the non-linear de-excitation of fluorescent dyes to overcome the…
Nov 30, 2011Story -
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Two-color STED Microscopy of Living Synapses using a Single Laser-beam Pair
The advent of superresolution microscopy has opened up new research opportunities into dynamic processes at the nanoscale inside living biological…
Nov 20, 2011Abstract -
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Modern Fluorescent Proteins and their Biological Applications
Here we present two review articles on fluorescent proteins and their biological applications. These first article reviews our current knowledge of…
Nov 18, 2011Abstract -
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Applications, Labeling Strategies and Fluorophores for Super-Resolution
The free online webinar on super-resolution presented by Leica Microsystems in association with Microscopy & Analysis took place on Tuesday, 15…
Nov 15, 2011Webinar -
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Restless Receptors
Synapses are the switch-points in our brain for information transmission, learning and memory. News studies and developments of imaging techniques…
Nov 01, 2010Story -
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The Missing Link to the Nanocosm of Life
Fully understanding the functionality and complexity of the human central nervous system remains one of the major open questions in modern science.…
Nov 01, 2010Story -
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A Guide to Super-Resolution Fluorescence Microscopy
For centuries, cell biology has been based on light microscopy and at the same time been limited by its optical resolution. However, several new…
Jul 18, 2010Abstract -
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Confocal Nanoscopy Goes Multicolor
Scientists strive to understand the architecture of life. They want to learn how biological structures are arranged in respect to one another.…
Feb 11, 2010Story -
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Interview with Stefan Hell – For me, Pioneering is …
Our interview partner on the topic of Pioneering is Prf. Stefan Hell, a scientific member of the Max Planck Society and director at the Max Planck…
Aug 31, 2008Story