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Role of Mucins and Glycosylation in Dry Eye Disease
This article shows how fast, high-contrast, and sharp imaging of stratified human corneal epithelial cells with THUNDER imaging technology for dry eye…
Sep 10, 2021Case Study -
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Skeletal Muscle Adaptation and Fibrotic Diseases
The mechanisms of how skeletal muscle adapts to fibrotic pathologies can be investigated more efficiently with fast, high-contrast imaging of C2C12…
Sep 02, 2021Case Study -
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Effects of Clearing Media on Tissue Transparency and Shrinkage
This study comprehensively evaluates the effects of different clearing media on tissue transparency and shrinkage by comparing freshly dissected…
Aug 19, 2021Case Study -
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Cortical Contributions to Complex Learning
This article describes the use of sharp, high contrast imaging to facilitate assessment of viral-construct placement in rat cortical brain tissue.…
Aug 17, 2021Case Study -
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Minimally Invasive Supermicrosurgery Technique
New techniques have emerged in recent years for lymphedema treatment, in particular minimally invasive lymphaticovenular anastomosis. Given the small…
Jun 30, 2021Case Study -
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Monitoring Immunosuppressive Mechanisms from Infection
This application note discusses the importance of fast, sensitive, and haze-free imaging for the monitoring of immunosuppression in mouse lung…
Jun 29, 2021Case Study -
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Studying Actin Cytoskeleton and Microfilament Assembly
This article demonstrates how actin microfilament assemblies can be clearly visualized with superior resolution at the plasma membrane of a cell using…
Jun 24, 2021Case Study -
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“Brains-In-A-Dish” from Induced Pluripotent Stem Cells (iPSCs)
This article discusses the benefits of using the THUNDER technology for imaging inside 3D human cortical brain organoids. These organoids are derived…
May 28, 2021Case Study -
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How to Quantify Changes in the Metabolic Status of Single Cells
Metabolic imaging based on fluorescence lifetime provides insights into the metabolic dynamics of cells, but its use has been limited as expertise in…
May 27, 2021Case Study -
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Developing Heart Pacemaker Cells from Cardiac Spheroids
During the last decade, 3D cell culture has been established as a more realistic model compared to classical 2D culture systems. Cells can develop…
May 26, 2021Case Study -
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Into the Third Dimension with "Wow Effect"- Observe Cells in 3D and Real-Time
Life is fast, especially for a cell. As a rule, cells should be examined under physiological conditions which are as close as possible to their…
May 19, 2021Case Study -
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Observing 3D Cell Cultures During Development
3D cell cultures, such as organoids and spheroids, give insights into cells and their interactions with their microenvironment. These 3D cell cultures…
May 19, 2021Case Study -
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Residual Fragment Assessment with the Proveo 8 Intraoperative OCT
In the brief video presented below, Dr. Rachid Tahiri, an ophthalmic surgeon at the Centre d’Ophtalmologie in Granville, France shares his experience…
Apr 12, 2021Case Study -
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Cataract Incision Analysis Using EnFocus Intraoperative OCT
Ophthalmic surgery requires high levels of accuracy and precision for optimal surgical maneuvers and tissue manipulation. Surgical microscopes play an…
Apr 12, 2021Case Study -
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Intraoperative OCT-Assisted Surgical Management of Proliferative Vitreoretinopathy
Proliferative vitreoretinopathy (PVR) is a plague to patients and their surgeons after recent rhegmatogenous retinal detachment (RD). Despite…
Apr 08, 2021Case Study -
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Studying Cell Division
Cell division is a biological process during which all cellular components must be distributed among the daughter cells. The division process requires…
Mar 09, 2021Case Study -
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Investigating Synapses in Brain Slices with Enhanced Functional Electron Microscopy
A fundamental question of neuroscience is: what is the relationship between structural and functional properties of synapses? Over the last few…
Mar 08, 2021Case Study -
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GLOW800 Augmented Reality Fluorescence in AVM (Arteriovenous Malformation) treatment
In this case study Prof. Dr. Feres Chaddad talks about the treatment of AVMs. It illustrates how the Augmented Reality Fluorescence GLOW800 can help…
Feb 18, 2021Case Study