The Microscopy Knowledge Portal

This article demonstrates how undecalcified mouse bone samples can be investigated in detail more easily and rapidly with a cryohistological method…

Creams, pastes, gels, emulsions, and tablets are ubiquitous across a wide range of manufacturing sectors from pharmaceuticals and consumer health…

This case study “Treatment of the Galassi type III arachnoid cyst with the M530 OHX surgical microscope from Leica Microsystems” documents the…

This article shows how fast, high-contrast, and sharp imaging of stratified human corneal epithelial cells with THUNDER imaging technology for dry eye…

The mechanisms of how skeletal muscle adapts to fibrotic pathologies can be investigated more efficiently with fast, high-contrast imaging of C2C12…

This study comprehensively evaluates the effects of different clearing media on tissue transparency and shrinkage by comparing freshly dissected…

This article describes the use of sharp, high contrast imaging to facilitate assessment of viral-construct placement in rat cortical brain tissue.…

New techniques have emerged in recent years for lymphedema treatment, in particular minimally invasive lymphaticovenular anastomosis. Given the small…

This application note discusses the importance of fast, sensitive, and haze-free imaging for the monitoring of immunosuppression in mouse lung…

This article demonstrates how actin microfilament assemblies can be clearly visualized with superior resolution at the plasma membrane of a cell using…

This article discusses the benefits of using the THUNDER technology for imaging inside 3D human cortical brain organoids. These organoids are derived…

Metabolic imaging based on fluorescence lifetime provides insights into the metabolic dynamics of cells, but its use has been limited as expertise in…

During the last decade, 3D cell culture has been established as a more realistic model compared to classical 2D culture systems. Cells can develop…

Life is fast, especially for a cell. As a rule, cells should be examined under physiological conditions which are as close as possible to their…

3D cell cultures, such as organoids and spheroids, give insights into cells and their interactions with their microenvironment. These 3D cell cultures…

In the brief video presented below, Dr. Rachid Tahiri, an ophthalmic surgeon at the Centre d’Ophtalmologie in Granville, France shares his experience…

Ophthalmic surgery requires high levels of accuracy and precision for optimal surgical maneuvers and tissue manipulation. Surgical microscopes play an…

Proliferative vitreoretinopathy (PVR) is a plague to patients and their surgeons after recent rhegmatogenous retinal detachment (RD). Despite…