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Science Lab

Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
Two-color caspase assay with tile scan. U2OS cells were treated with the nuclear marker DRAQ5 (magenta) and CellEvent™ (yellow).

Following Multiple Events during Staurosporine Apoptosis

Coming next on MicaCam - Livestream on 19th October 2022 - In this episode of MicaCam, we show how adding additional markers to an apoptosis kit can markedly increase the amount of information a…
Analysis of an aneurysm with Virtual Reality. Image courtesy of Prof. Raphael Guzman.

Digitalization in Neurosurgical Planning and Procedures

Learn about Augmented Reality, Virtual Reality and Mixed Reality in neurosurgery and how they can help overcome challenges.
Brain tumor surgical planning leveraging Augmented Reality. Image courtesy of Prof. Philippe Bijlenga.

Augmented Reality Assisted Navigation in Neuro-Oncological Surgery

In neuro-oncological surgery, new technologies such as Augmented Reality are helping to improve surgical precision enabling a precise trajectory, conformational resection, the absence of collateral…
Untreated Hela Kyoto cells stained to show the nucleus (Hoechst, blue), the cis-golgi matrix protein GM130 (AF488, green), and the trans-golgi network membrane protein TGN46 (AF647, red).

Golgi Organizational Changes in Response to Cell Stress

VIDEO ON DEMAND - In this episode of MicaCam, our special guest George Galea from EMBL Heidelberg will look at HeLa Kyoto cells treated with various chemotherapeutic agents to investigate their effect…
Protist Paramecium (Paramecium tetraurelia) stained to show the nucleus

AI-Enabled Spatial Analysis of Complex 3D Datasets

VIDEO ON DEMAND - This edition of MicaCam offers practical advice on the extraction of publication grade insights from microscopy images. Our special guest Luciano Lucas (Leica Microsystems) will…
Visualization of an AVM with the Leica FL560 fluorescein fluorescence module

Benefits of Fluorescence in Vascular Neurosurgery

Fluorescein and ICG fluorescence videoangiography have transformed the experience of vascular neurosurgeons, providing an intraoperative view with enriched information. During the Leica 2021…
Image of a single slice taken from a zebrafish heart showing the ventricle with an injury in the lower area. Nuclei of all cells are indicated with blue, nuclei of the cardiomyocyte heart muscle cells with green, and the proliferating cells with red. Courtesy of Laura Peces-Barba Castaño, Max Planck Institute for Heart and Lung Research, Germany.

Imaging of Cardiac Tissue Regeneration in Zebrafish

Learn how to image cardiac tissue regeneration in zebrafish focusing on cell proliferation and response during recovery. MicaCam Episode 04 with Laura Peces-Barba Castaño from the Max Planck…

How Does The Cytoskeleton Transport Molecules?

VIDEO ON DEMAND - See how 3D cysts derived from MDCK cells help scientists understand how proteins are transported and recycled in tissues and the role of the cytoskeleton in this transport.
Developing zebrafish (Danio rerio) embryo, from sphere stage to somite stages.

Studying Early Phase Development of Zebrafish Embryos

VIDEO ON DEMAND - This second edition of MicaCam focuses on combining widefield and confocal imaging to study the early-stage development of zebrafish embryos (Danio rerio), from oocyte to…
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