

The Microscopy Knowledge Portal
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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Topics – A Vast Amount of Expert Knowledge
- Basics in Microscopy

- Confocal Microscopy

- Digital Microscopy

- Dentistry

- EM Sample Preparation

- Fluorescence Microscopy

- Light Sheet Microscopy

- Neurosurgery

- Optical Coherence Tomography

- Super-Resolution

- Stereo Microscopy

- Surface Metrology

- Quality Assurance

- Otolaryngology (ENT)

- Ophthalmology

- Plastic Reconstructive

- Widefield Microscopy

- More
Latest Articles

Improvement of Imaging Techniques to Understand Organelle Membrane Cell Dynamics
Understanding cell functions in normal and tumorous tissue is a key factor in advancing research of potential treatment strategies and understanding why some treatments might fail. Single-cell…Read article
How OCT-guided eye surgery can help you to Focus on Perfection
Watch the successful clinical online symposium on-demand. Find out what Dr. Parolini says about the benefits of OCT-guided ophthalmic surgery. She presents clinical cases and shares her experience…Read article
Microscopy Enhanced Navigation in Neurosurgery
Neurosurgical procedures are very complex and delicate, especially when they involve craniotomy. Surgeons need to be extremely focused and concentrated throughout. Navigation plays an essential role,…Read article
Advancing Cell Biology with Cryo-Correlative Microscopy
Correlative light and electron microscopy (CLEM) advances biological discoveries by merging different microscopes and imaging modalities to study systems in 4D. Combining fluorescence microscopy with…Read article
Writing the NIH Research (R01) grant: Strategies for Success
With highly competitive NIH budgets and ever-increasing restrictions on federal spending, getting noticed and winning an NIH R grant is far more difficult and highly competitive than it has ever been.…Read article
Pursuing private foundation and corporate grant opportunities in Life Science Research
Devon Brewer describes the essentials for pursuing research grants from private foundations and corporations.Read article
High-pressure freezing: Revealing functional mechanisms of synaptic transmission
Learn more about applying optogenetic stimulation in the EM ICE and how this technology has the potential to reveal structural and functional mechanisms of synaptic transmission. Get a detailed…Read article
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
Obtaining high-quality data and images from thick 3D samples is challenging using traditional widefield microscopy because of the contribution of out-of-focus light. In this webinar, Falco Krüger…Read article
Cornea Webinar Series: DMEK, DSAEK, and DALK cases
Exclusive 2-part webinar series by Dr. Jod S Mehta, distinguished Professor, Duke-NUS, Singapore National Eye Center. Learn DMEK, complicated DSAEK, DALK surgery, indications, techniques, and the…Read article
How to Conduct Standard-Compliant Analysis of Non-Metallic Inclusions in Steel
This webinar will provide an overview of the significance of non-metallic inclusions in steel and outline the important global standards for rating the quality of steel and difficulties that arise in…Read article
Workflows and Instrumentation for Cryo-electron Microscopy
Cryo-electron microscopy is an increasingly popular modality to study the structures of macromolecular complexes and has enabled numerous new insights in cell biology. In recent years, cryo-electron…Read article
Time-resolved STED microscopy
Introduced more than 30 years ago, stimulated emission depletion (STED) microscopy has raised to a standard and widely used method for imaging in the life sciences. Thanks to continuous technological…Read article
Advanced Techniques in Cataract and Refractive Surgery
In this webinar Dr. Thompson and Dr. Moshirfar will explain how Leica microscopes aid in procedures such as Centration of Multifocal IOLs and corneal inlays such as Kamra and Lenticular Grafts used in…Read article
Augmented Reality and Fluorescence: Clinical Uses in Cerebrovascular and Skull Base Neurosurgery
In this webinar Dr. Bendok and Dr. Morcos explain how Augmented Reality and Fluorescence can enhance visualization and support surgical decision making. They present first-hand experience of the GLOW…Read article
From dentistry to micro-dentistry: See more – optimize your dental workflow
Endodontics expert Fabio Gorni shares his vast experience in micro-dentistry and provides answers to questions of the webinar participants at the end of the recording. This webinar allows you to…Read article


