Leica Science Lab - Tag : Super-Resolution https://www.leica-microsystems.com//science-lab/tag/?tx_leicaacademy_pi4%5Baction%5D=show&tx_leicaacademy_pi4%5Bcontroller%5D=Tag&tx_leicaacademy_pi4%5Btag%5D=1267&cHash=2c919c3122f2f769873ea24950c9b7cd Article tagged with Super-Resolution en-US https://www.leica-microsystems.com/31232 Widefield Microscopy Fluorescence Microscopy Stereo Microscopy Live-Cell Imaging An Introduction to Computational Clearing Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The most common methods used to remove background noise from WF images are rolling ball and sliding paraboloid. Recently, Leica Microsystems introduced their own background subtraction method called Instant Computational Clearing (ICC), which is present in all Leica THUNDER WF imaging platforms. https://www.leica-microsystems.com/science-lab/an-introduction-to-computational-clearing/ Thu, 01 Oct 2020 09:00:00 +0000 PhD Vikram Kohli, Dr. Levi Felts, PhD James M. Marr, Dr. Jan Schumacher, Dr. Oliver Schlicker https://www.leica-microsystems.com/30582 Super-Resolution Time-resolved STED microscopy Introduced more than 30 years ago, stimulated emission depletion (STED) microscopy has raised to a standard and widely used method for imaging in the life sciences. Thanks to continuous technological progress, STED microscopy can now provide effective sub-diffraction spatial resolution, while preserving most of the useful aspects of fluorescence microscopy, such as optical sectioning, molecular specificity and sensitivity, and live-cell compatibility. https://www.leica-microsystems.com/science-lab/time-resolved-sted-microscopy/ Thu, 03 Sep 2020 12:04:00 +0000 Ph.D. Giuseppe Vicidomini https://www.leica-microsystems.com/30136 Confocal Microscopy Fluorescence Microscopy Super-Resolution CLEM TIRF Microscopy Widefield Microscopy Live-Cell Imaging Laser Microdissection Microscopy in Virology The coronavirus SARS-CoV-2, causing the Covid-19 disease effects our world in all aspects. Research to find immunization and treatment methods, in other words to fight this virus, gained highest priority in 2020. Microscopes play a significant role in this kind of research. To understand the underlaying principles of receptor binding, genome release, replication, assembly, and virus budding, as well as the response of our immune system, different methodologies and microscopes can be used. This article summarizes why microscopy is an important tool in virology and infection biology and gives examples for different microscopy technologies and their applications in these research fields. https://www.leica-microsystems.com/science-lab/microscopy-in-virology/ Mon, 13 Jul 2020 12:13:00 +0000 Dr. Christoph Greb