Leica Science Lab - Tag : Diabetes https://www.leica-microsystems.com//science-lab/tag/tags/diabetes/show/Tag/ Article tagged with Diabetes en-US https://www.leica-microsystems.com/18176 White Confocal ERK2 and Akt are Negative Regulators of Insulin and Tumor Necrosis Factor-α Stimulated VCAM-1 Expression in Rat Aorta Endothelial Cells Diabetes is quickly becoming the most widespread disorder in the Western world. Among the most prevalent effects of diabetes is atherosclerosis, which in turn is driven in part by inflammation. Both insulin and Tumor Necrosis Factor-alpha (TNFα) increase the presence of Vascular Cellular Adhesion Molecule-1 (VCAM-1) expression. The aim of this study is to determine the effects of downregulating Extracellular signal-Regulated Kinase-2 (ERK2) and Akt on insulin and TNFa-stimulated VCAM-1 expression. https://www.leica-microsystems.com//science-lab/erk2-and-akt-are-negative-regulators-of-insulin-and-tumor-necrosis-factor-a-stimulated-vcam-1-expression-in-rat-aorta-endothelial-cells/ Wed, 01 Jun 2016 12:14:00 +0000 https://www.leica-microsystems.com/14389 Super-Resolution TIRF Microscopy Video Interview with William Hughes William Hughes works at the Garvan Institute of Medical Research, Sydney (Australia). In his Lab Head position he is interested in the causes of diabetes particularly looking at changes in exocytic behavior of pancreatic beta cells as well as fat and muscle cells. TIRF microscopy is predestined for researchers looking at cellular processes near the cytoplasmic membrane. https://www.leica-microsystems.com//science-lab/video-interview-with-william-hughes/ Wed, 24 Sep 2014 15:14:00 +0000 Dr. William Hughes, Dipl. oec.-troph. Anja Schué, Dr. Christoph Greb