Leica Science Lab - Tag : Endothelial Cells https://www.leica-microsystems.com//science-lab/tag/tags/endothelial-cells/show/Tag/ Article tagged with Endothelial Cells en-US https://www.leica-microsystems.com/18952 Super-Resolution Live-Cell Imaging Image Restoration and Deconvolution Discovery of Novel Peptides Targeting Pro-Atherogenic Endothelium in Disturbed Flow Regions -Targeted siRNA Delivery to Pro-Atherogenic Endothelium in vivo Application example of HyVolution Super-Resolution - Atherosclerosis occurs preferentially in arterial regions exposed to disturbed blood flow. Targeting these pro-atherogenic regions is a potential anti-atherogenic therapeutic approach, but it has been extremely challenging. Here, using in vivo phage display approach and the partial carotid ligation model of flow-induced atherosclerosis in mouse, we identified novel peptides that specifically bind to endothelial cells (ECs) exposed to disturbed flow condition in pro-atherogenic regions. https://www.leica-microsystems.com//science-lab/discovery-of-novel-peptides-targeting-pro-atherogenic-endothelium-in-disturbed-flow-regions-targeted-sirna-delivery-to-pro-atherogenic-endothelium-in-vivo/ Thu, 10 Nov 2016 15:28:00 +0000 https://www.leica-microsystems.com/13913 Laser Microdissection Glucose-Regulated Protein 78 (Grp78) Confers Chemoresistance to Tumor Endothelial Cells under Acidic Stress This study was designed to investigate the activation of the unfolded protein response (UPR) in tumor associated endothelial cells (TECs) and its association with chemoresistance during acidic pH stress. https://www.leica-microsystems.com//science-lab/glucose-regulated-protein-78-grp78-confers-chemoresistance-to-tumor-endothelial-cells-under-acidic-stress/ Mon, 21 Jul 2014 17:16:00 +0000